Evidence map›Paper›PMID 37366475›Full record

ArticleCureus2023

Antisynthetase Syndrome With Paraneoplastic Antibodies.

Ashbina Pokharel, Ioannis Karageorgiou, Indira Acharya, Tucker Billups, Judith Bateman

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 85% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Ashbina PokharelInternal Medicine, Beaumont Hospital, Royal Oak, USA.
Ioannis KarageorgiouInternal Medicine, Beaumont Hospital, Royal Oak, USA.
Indira AcharyaInternal Medicine, MedStar Union Memorial Hospital, Baltimore, USA.
Tucker BillupsInternal Medicine, Beaumont Hospital, Royal Oak, USA.
Judith BatemanRheumatology, Beaumont Hospital, Royal Oak, USA.
Beaumont Hospital · USBeaumont Hospital, Royal Oak · USMedStar Union Memorial Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antisynthetase syndrome (ASyS) is an uncommon systemic autoimmune disorder characterized by the presence of autoantibodies targeting aminoacyl-transfer RNA (tRNA) synthetase. The syndrome displays a diverse range of clinical manifestations affecting multiple organs, thereby posing a diagnostic challenge. In this report, we present an unusual case of a patient diagnosed with ASyS, displaying positive anti-PL-12 antibodies along with paraneoplastic antibodies. To the best of our knowledge, this is the first documented case in the existing literature describing ASyS with the presence of anti-PL-12 antibodies and concomitant paraneoplastic antibodies in the context of ductal carcinoma in situ.

Indexed as

antisynthetase syndromeautoimmune diseaseductal carcinoma in-situinterstitial lung diseaseparaneoplastic syndrome

Identifiers

PMID37366475
PMCPMC10290814
OpenAlexW4380633051

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.