ArticleJournal of veterinary internal medicine
Effect of time of sample collection after onset of diarrhea on fecal microbiota composition of calves.
Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 8 citations in OpenAlex.
- Differences in gut microbiome of Hanwoo (Korean indigenous cattle) calves as driven by bovine rotavirus and bovine coronavirus infection.Journal of animal science and technology · 2026Article
- Identification of gut microbiota features of diarrheic calves using the full-length 16S rRNA gene amplicon sequencing and machine learning.Animal microbiome · 2026Article
- Analysis of differences in gut microbiota structure and function in Bactrian camels under different breeding patterns from northern and southern Xinjiang, China.Frontiers in veterinary science · 2026Article
- Exploring colostrum microbiota and its influence on early calf gut microbiota development using full-length 16S rRNA gene metabarcoding.Scientific reports · 2025Article
- The gastrointestinal tract microbiome of Holstein × Angus cross cattle is negatively impacted by the pre-harvest process.Applied and environmental microbiology · 2025Article
- Changes in the gut microbiome due to diarrhea in neonatal Korean indigenous calves.Frontiers in microbiology · 2025Article
- Fecal microbiota of diarrheic calves: Before, during, and after recovering from disease.Journal of veterinary internal medicineArticle
- Effect of time of sample collection after onset of diarrhea on fecal microbiota composition of calves.Journal of veterinary internal medicineArticle
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundThe effect of time of sample collection after onset of diarrhea on the fecal microbiota composition of calves is unknown.
objectiveCompare the fecal microbiota of calves with diarrhea onset on the day of sampling (D <24h), and calves having had diarrhea for >24 to 48 hours (D 24-48h). ANIMALS: Thirty-one diarrheic calves (20 D <24h and 11 D 24-48h), 3 to 7 days of age.
methodsCross-sectional study. Diarrhea was defined as a calf with loose feces or watery feces. Assessment of the fecal microbiota was performed by sequencing of 16S ribosomal RNA gene amplicons.
resultsRichness and diversity were not statistically different between D <24h and D 24-48h (P > .05), but bacterial membership and structure differed significantly (AMOVA, P < .001 for both comparisons). Linear discriminant analysis effect size (LefSe) showed an enrichment of Faecalibacterium, Phocaeicola, Lachnospiracea, and Lactobacillus in the feces of D <24h calves, whereas Escherichia/Shigella, Ligilactobacillus, Clostridium_Sensu_Stricto, Clostridium_Incerta_Sedis, and Enterococcus were enriched in the D 24-48h calves. CONCLUSION AND CLINICAL IMPORTANCE: Rapid changes in fecal microbiota occur during the first 48 hours of diarrhea with an enrichment of lactic acid-producing bacteria in D <24h followed by an enrichment in Escherichia/Shigella and Clostridium spp. in D 24-48h. The time from diarrhea onset to sampling appears to affect the bacterial composition. Researchers should standardize times for fecal collection based on the time of diarrhea.
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Registered trials
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