ArticleJournal of the International Neuropsychological Society : JINS2024
Cortical thickness moderates intraindividual variability in prefrontal cortex activation patterns of older adults during walking.
Article in Journal of the International Neuropsychological Society : JINS, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed, 1 citations in OpenAlex.
- Mediating effect of cognitive reserve on associations between processing speed and memory in older adults with and without multiple sclerosis.Neuropsychology · 2026Article
- The ageing brain: Cortical overactivation - How does it evolve?The Journal of physiology · 2026Review
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveIncreased intraindividual variability (IIV) in behavioral and cognitive performance is a risk factor for adverse outcomes but research concerning hemodynamic signal IIV is limited. Cortical thinning occurs during aging and is associated with cognitive decline. Dual-task walking (DTW) performance in older adults has been related to cognition and neural integrity. We examined the hypothesis that reduced cortical thickness would be associated with greater increases in IIV in prefrontal cortex oxygenated hemoglobin (HbO
methodParticipants were 55 healthy community-dwelling older adults (mean age = 74.84, standard deviation (
resultsAnalyses revealed that thinner cortex in several regions was associated with greater increases in HbO
conclusionsConsistent with neural inefficiency, reduced cortical thickness in the PFC and throughout the cerebral cortex was associated with increases in HbO
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