ArticleCardiovascular diabetology2023
The predictive value of atherogenic index of plasma for cardiovascular outcomes in patients with acute coronary syndrome undergoing percutaneous coronary intervention with LDL-C below 1.8mmol/L.
Article in Cardiovascular diabetology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 4 of them syntheses that pooled it.
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Who cites it
32 citing papers in PubMed, 4 syntheses or guidelines pooled it, 51 citations in OpenAlex.
- Association between atherogenic index of plasma and various metabolic conditions: an umbrella review on meta-analyses.BMC cardiovascular disorders · 2025Pooled it
- Atherogenic index of plasma and the clinical outcome of patients with acute coronary syndrome: a meta-analysis.Annals of medicine · 2025Pooled it
- Atherogenic index of plasma and coronary artery disease: a systematic review and meta-analysis of observational studies.Cardiovascular diabetology · 2025Pooled it
- The association of atherogenic index of plasma with cardiovascular outcomes in patients with coronary artery disease: A systematic review and meta-analysis.Cardiovascular diabetology · 2024Pooled it
- Association between the atherogenic index of plasma trajectory and risk of cardiovascular diseases among hypertensive patients: a prospective cohort study.Cardiovascular diabetology. Endocrinology reports · 2026Article
- Prognostic value of the atherogenic index of plasma in patients with multivessel coronary disease undergoing CABG: a retrospective cohort study.Lipids in health and disease · 2026Article
- The joint association of the combined triglyceride-glucose index and atherogenic index of plasma with hypertension on stroke risk across different glycemic status: a prospective cohort study.Cardiovascular diabetology · 2026Article
- Potential Value of Novel Lipid-Derived Indicator as a Biomarker for Nonarteritic Anterior Ischemic Optic Neuropathy.Translational vision science & technology · 2026Article
- Prognostic value of the AIP index in patients with severe aortic stenosis undergoing transcatheter aortic valve replacement.Frontiers in nutrition · 2026Article
- The prognostic value of atherogenic index of plasma and thin-cap fibroatheroma among patients with STEMI: an optical coherence tomography prospective cohort study of real world.Cardiovascular diabetology · 2025Observational
- Effects of statins on major adverse cardiovascular events, metabolic and inflammatory parameters in patients with hepatitis B virus comorbid with cardiovascular disease.Cardiovascular diagnosis and therapy · 2025Article
- Association between cardiometabolic phenotypes with atherogenic index of plasma: a cross-sectional study from the Azar cohort population.BMC cardiovascular disorders · 2025Article
- Observational
- Association Between Atherogenic Index of Plasma and Clinical Outcomes in Peritoneal Dialysis Population.Journal of clinical medicine · 2025Article
- The Interplay of Cardiometabolic Syndrome Phenotypes and Cardiovascular Risk Indices in Patients Diagnosed with Diabetes Mellitus.International journal of molecular sciences · 2025Article
- Associations of the atherogenic index of plasma with 28-day in-hospital mortality in patients with acute myocardial infarction: a retrospective cohort study from the eICU.Lipids in health and disease · 2025Article
- Atherogenic index of plasma and triglyceride-glucose index mediate the association between stroke and all-cause mortality: insights from the lipid paradox.Lipids in health and disease · 2025Article
- Atherogenic Index of Plasma (AIP) as a Long-Term Prognostic Factor Following CABG: Unveiling Insights From a Large-Scale Tertiary Center Registry Analysis.Health science reports · 2025Article
- Relationship between dietary intake and atherogenic index of plasma in cardiometabolic phenotypes: a cross-sectional study from the Azar cohort population.Journal of health, population, and nutrition · 2025Article
- Relationship between traditional and non-traditional obesity parameters and diabetes and early-onset diabetes: an analysis based on a large cohort.Frontiers in endocrinology · 2025Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe potential predictive significance of atherogenic index of plasma (AIP) for cardiovascular outcomes in patients with acute coronary syndrome (ACS) and who have undergone percutaneous coronary intervention (PCI), with low-density lipoprotein-cholesterol (LDL-C) below 1.8mmol/L, has not been well explored.
methodsThe retrospective cohort analysis included 1,133 patients with ACS and LDL-C levels below 1.8mmol/L who underwent PCI. AIP is calculated as log (triglyceride/high-density lipoprotein-cholesterol). Patients were divided into two groups according to the median value of AIP. The primary endpoint was major adverse cardiovascular and cerebrovascular events (MACCEs), a composite of all-cause death, nonfatal myocardial infarction, ischemic stroke or unplanned repeat revascularization. The association between AIP and the prevalence of MACCE was evaluated using multivariable Cox proportional hazard models.
resultsOver a median follow-up of 26 months, the incidence of MACCE was higher in the high AIP group compared to the low AIP group (9.6% vs. 6.0%, P log-rank = 0.020), and the difference was mainly derived from an increased risk of unplanned repeat revascularization (7.6% vs. 4.6%, P log-rank = 0.028). After adjusting for multiple variables, elevated AIP was independently associated with an increased risk of MACCE, regardless of whether AIP was considered a nominal or continuous variable (hazard ratio [HR] 1.62, 95% confidence interval [CI] 1.04-2.53 or HR 2.01, 95% CI 1.09-3.73).
conclusionsThe present study demonstrates that AIP is a significant predictor of adverse outcomes in ACS patients undergoing PCI with LDL-C < 1.8mmol/L. These results suggest that AIP may offer supplementary prognostic information for ACS patients with optimally managed LDL-C levels.
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