Evidence map›Paper›PMID 37365411›Full record

ReviewBrain structure & function2023

Mixed methodology in human brain research: integrating MRI and histology.

Anneke Alkemade, Rosa Großmann, Pierre-Louis Bazin, Birte U Forstmann

Abstract readReview
In one paragraph

Review in Brain structure & function, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Beyond Macrostructure: Is There a Role for Radiomics Analysis in Neuroimaging ?Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2024
    Review
  11. Imaging of the superficial white matter in health and disease.Imaging neuroscience (Cambridge, Mass.) · 2024
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anneke AlkemadeIntegrative Model-Based Cognitive Neuroscience Unit, Department of Psychology, University of Amsterdam, Amsterdam, The Netherlands. jmalkemade@gmail.com.ORCID http://orcid.org/0000-0002-3234-353X
Rosa GroßmannIntegrative Model-Based Cognitive Neuroscience Unit, Department of Psychology, University of Amsterdam, Amsterdam, The Netherlands.
Pierre-Louis BazinIntegrative Model-Based Cognitive Neuroscience Unit, Department of Psychology, University of Amsterdam, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0002-0141-5510
Birte U ForstmannIntegrative Model-Based Cognitive Neuroscience Unit, Department of Psychology, University of Amsterdam, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0002-1005-1675

Funding

European Research Council 864750
6 · The paper itself

Abstract

Postmortem magnetic resonance imaging (MRI) can provide a bridge between histological observations and the in vivo anatomy of the human brain. Approaches aimed at the co-registration of data derived from the two techniques are gaining interest. Optimal integration of the two research fields requires detailed knowledge of the tissue property requirements for individual research techniques, as well as a detailed understanding of the consequences of tissue fixation steps on the imaging quality outcomes for both MRI and histology. Here, we provide an overview of existing studies that bridge between state-of-the-art imaging modalities, and discuss the background knowledge incorporated into the design, execution and interpretation of postmortem studies. A subset of the discussed challenges transfer to animal studies as well. This insight can contribute to furthering our understanding of the normal and diseased human brain, and to facilitate discussions between researchers from the individual disciplines.

Indexed as

BrainMagnetic Resonance ImagingAnimalsHistological TechniquesHumansCo-registrationHistologyMRIPostmortemReconstructions

Identifiers

PMID37365411
PMCPMC10335951

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.