Evidence map›Paper›PMID 37365194›Full record

ArticleScientific reports2023

Cytokine profiles in adults with imported malaria.

Charles de Roquetaillade, Cédric Laouenan, Jean-Paul Mira, Carine Roy, Marie Thuong, Élie Azoulay, Didier Gruson, Frédéric Jacobs, Juliette Chommeloux, François Raffi and 8 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 15 institutions in 1 country.

Charles de RoquetailladeDepartment of Anesthesiology and Critical Care, Hôpital Lariboisière, FHU PROMICE, DMU Parabol, AP-HP Nord, Paris, France. charles.de-roquetaillade@aphp.fr.
Cédric LaouenanDépartement Epidémiologie Biostatistiques et Recherche Clinique, AP-HP, INSERM, Centre d'Investigation Clinique-Epidémiologie Clinique 1425, Hôpital Bichat, Paris, France.
Jean-Paul MiraService de medecine intensive-reanimation, Hôpital Cochin, AP-HP Centre, Paris, France.
Carine RoyDépartement Epidémiologie Biostatistiques et Recherche Clinique, AP-HP, INSERM, Centre d'Investigation Clinique-Epidémiologie Clinique 1425, Hôpital Bichat, Paris, France.
Marie ThuongService de medecine intensive-reanimation, Centre Hospitalier René Dubos, Pontoise, France.
Élie AzoulayService de medecine intensive-reanimation, Hôpital Saint-Louis, Hôpitaux Universitaires Paris-Nord, AP-HP, Paris, France.
Didier GrusonService de medecine intensive-reanimation, Hôpital Pellegrin-Tripode, Bordeaux, France.
Frédéric JacobsService de medecine intensive-reanimation, Hôpital Antoine Béclère, Université Paris-Saclay, AP-HP, Clamart, France.
Juliette ChommelouxService de medecine intensive reanimation, Institut de Cardiologie, ICAN, Groupe Hospitalier Pitié-Salpêtrière, Sorbonne Université, AP-HP, Paris, France.
François RaffiCHU de Nantes, CIC UIC 1413 Inserm, Nantes, France.
Laurent HocquelouxService de maladies infectieuses, Centre Hospitalier Régional d'Orléans, Orléans, France.
Patrick ImbertCentre de vaccinations internationales, Hôpital d'instruction des armees Bégin, Saint-Mandé, France.
Vincent JeantilsService de maladies infectieuses, Hôpital Jean Verdier, AP-HP, Bondy, France.
Jean-Luc DelassusService de medecine interne et de maladies infectieuses, Centre hospitalier intercommunal Robert-Ballanger, Aulnay-sous-Bois, France.
Sophie MatheronService de maladies infectieuses et tropicales, Hôpital Bichat, GHU Paris Nord, AP-HP, Paris, France.
Catherine FittingUnité cytokines et inflammation, Institut Pasteur, Paris, France.
Jean-François TimsitService de medecine intensive et reanimation (MI2), Hôpital Bichat, Paris, France.
Fabrice BruneelService de reanimation, Centre Hospitalier de Versailles, Hôpital André Mignot, Le Chesnay, France.
Assistance Publique – Hôpitaux de Paris · FRHôpital Bichat-Claude-Bernard · FRCentre hospitalier régional d'Orléans · FRCentre Hospitalier René-Dubos · FRCentre hospitalier Robert-Ballanger · FRDélégation Paris 7 · FRHôpital André Mignot · FRHôpital d'Instruction des Armées Bégin · FRHôpital Lariboisière · FRHôpital Pellegrin · FRHôpitaux Universitaires Paris-Ouest · FRInserm · FRInstitut Cochin · FRInstitut Pasteur · FRUniversité Paris-Saclay · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increase in worldwide travel is making imported malaria a growing health concern in non-endemic countries. Most data on the pathophysiology of malaria come from endemic areas. Little is known about cytokine profiles during imported malaria. This study aimed at deciphering the relationship between cytokine host response and malaria severity among imported cases in France. This study reports cytokine profiles in adults with Plasmodium falciparum malaria included in the PALUREA prospective study conducted between 2006 and 2010. The patients were classified as having uncomplicated malaria (UM) or severe malaria (SM), with this last further categorized as very severe malaria (VSM) or less severe malaria (LSM). At hospital admission, eight blood cytokines were assayed in duplicate using Luminex

Indexed as

MalariaMalaria, FalciparumAdultCytokinesHumansInterleukin-10Interleukin-2Interleukin-4Plasmodium falciparumProspective StudiesTumor Necrosis Factor-alphaCytokinesInterleukin-10Interleukin-2Interleukin-4Tumor Necrosis Factor-alpha

Identifiers

PMID37365194
PMCPMC10293253
OpenAlexW4382020860

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.