Evidence map›Paper›PMID 37365172›Full record

ArticleNature communications2023

Patterns and determinants of the global herbivorous mycobiome.

Casey H Meili, Adrienne L Jones, Alex X Arreola, Jeffrey Habel, Carrie J Pratt, Radwa A Hanafy, Yan Wang, Aymen S Yassin, Moustafa A TagElDein, Christina D Moon and 22 more

Abstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Description ofInternational journal of systematic and evolutionary microbiology · 2026
    Article
  5. Diversity and community structure of anaerobic gut fungi in camels.bioRxiv : the preprint server for biology · 2026
    Article
  6. Article
  7. Description ofbioRxiv : the preprint server for biology · 2025
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. International journal of systematic and evolutionary microbiology · 2025
    Article
  13. Article
  14. Article
  15. Exploitation of Biodiversity in Bioeconomy: Examples, Opportunities, and Challenges.Advances in biochemical engineering/biotechnology · 2025
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

32 authors.

Casey H MeiliOklahoma State University, Department of Microbiology and Molecular Genetics, Stillwater, OK, USA.ORCID 0000-0003-0379-3440
Adrienne L JonesOklahoma State University, Department of Microbiology and Molecular Genetics, Stillwater, OK, USA.
Alex X ArreolaOklahoma State University, Department of Microbiology and Molecular Genetics, Stillwater, OK, USA.
Jeffrey HabelOklahoma State University, Department of Microbiology and Molecular Genetics, Stillwater, OK, USA.
Carrie J PrattOklahoma State University, Department of Microbiology and Molecular Genetics, Stillwater, OK, USA.ORCID 0000-0003-1545-2467
Radwa A HanafyOklahoma State University, Department of Microbiology and Molecular Genetics, Stillwater, OK, USA.
Yan WangDepartment of Biological Sciences, University of Toronto Scarborough, Toronto, ON, Canada.ORCID 0000-0002-5950-8904
Aymen S YassinDepartment of Microbiology and Immunology, Faculty of Pharmacy, Cairo University, Cairo, Egypt.ORCID 0000-0002-4423-164X
Moustafa A TagElDeinDepartment of Microbiology and Immunology, Faculty of Pharmacy, Cairo University, Cairo, Egypt.
Christina D MoonAgResearch Ltd, Grasslands Research Centre, Palmerston North, New Zealand.
Peter H JanssenAgResearch Ltd, Grasslands Research Centre, Palmerston North, New Zealand.ORCID 0000-0002-1022-3502
Mitesh ShresthaDepartment of Applied Microbiology and Food Technology, Research Institute for Bioscience and Biotechnology (RIBB), Kathmandu, Nepal.
Prajwal RajbhandariDepartment of Applied Microbiology and Food Technology, Research Institute for Bioscience and Biotechnology (RIBB), Kathmandu, Nepal.ORCID 0000-0003-3159-8263
Magdalena NaglerUniversität Innsbruck, Faculty of Biology, Department of Microbiology, Innsbruck, Austria.ORCID 0000-0002-4165-7290
Julia M VinzeljUniversität Innsbruck, Faculty of Biology, Department of Microbiology, Innsbruck, Austria.ORCID 0000-0002-6139-2795
Sabine M PodmirsegUniversität Innsbruck, Faculty of Biology, Department of Microbiology, Innsbruck, Austria.
Jason E StajichDepartment of Microbiology and Plant Pathology, University of California, Riverside, Riverside, CA, USA.ORCID 0000-0002-7591-0020
Arthur L GoetschLangston University, Langston, OK, USA.
Jerry HayesLangston University, Langston, OK, USA.
Diana YoungBavarian State Research Center for Agriculture, Freising, Germany.
Katerina FliegerovaInstitute of Animal Physiology and Genetics Czech Academy of Sciences, Prague, Czechia.ORCID 0000-0001-9439-8168
Diego Javier GrilliÁrea de Microbiología, Facultad de Ciencias Médicas, Universidad Nacional de Cuyo, Mendoza, Argentina.
Roman VodičkaPrague Zoo, Prague, Czechia.
Giuseppe MonielloDepartment of Veterinary Medicine, University of Sassari, Sardinia, Italy.
Silvana MattielloUniversity of Milan, Dept. of Agricultural and Environmental Sciences, Milan, Italy.ORCID 0000-0003-1885-949X
Mona T KashefDepartment of Microbiology and Immunology, Faculty of Pharmacy, Cairo University, Cairo, Egypt.
Yosra I NagyDepartment of Microbiology and Immunology, Faculty of Pharmacy, Cairo University, Cairo, Egypt.
Joan A EdwardsAnaerobic Fungi Network, Kerkdriel, Netherlands.ORCID 0000-0003-0759-633X
Sumit Singh DagarBioenergy Group, Agharkar Research Institute, Pune, India.
Andrew P FooteOklahoma State University, Department of Animal and Food Sciences, Stillwater, OK, USA.ORCID 0000-0002-7995-1540
Noha H YoussefOklahoma State University, Department of Microbiology and Molecular Genetics, Stillwater, OK, USA. noha@okstate.edu.ORCID 0000-0001-9159-3785
Mostafa S ElshahedOklahoma State University, Department of Microbiology and Molecular Genetics, Stillwater, OK, USA. mostafa@okstate.edu.ORCID 0000-0002-1067-1647

Funding

Austrian Science Fund FWF I 3808
6 · The paper itself

Abstract

Despite their role in host nutrition, the anaerobic gut fungal (AGF) component of the herbivorous gut microbiome remains poorly characterized. Here, to examine global patterns and determinants of AGF diversity, we generate and analyze an amplicon dataset from 661 fecal samples from 34 mammalian species, 9 families, and 6 continents. We identify 56 novel genera, greatly expanding AGF diversity beyond current estimates (31 genera and candidate genera). Community structure analysis indicates that host phylogenetic affiliation, not domestication status and biogeography, shapes the community rather than. Fungal-host associations are stronger and more specific in hindgut fermenters than in foregut fermenters. Transcriptomics-enabled phylogenomic and molecular clock analyses of 52 strains from 14 genera indicate that most genera with preferences for hindgut hosts evolved earlier (44-58 Mya) than those with preferences for foregut hosts (22-32 Mya). Our results greatly expand the documented scope of AGF diversity and provide an ecologically and evolutionary-grounded model to explain the observed patterns of AGF diversity in extant animal hosts.

Indexed as

MycobiomeAnimalsBiological EvolutionDigestive SystemFecesMammalsPhylogeny

Identifiers

PMID37365172
PMCPMC10293281

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.