Evidence map›Paper›PMID 37364998›Full record

ArticleeNeuro2023

A Selective Projection from the Subthalamic Nucleus to Parvalbumin-Expressing Interneurons of the Striatum.

Krishnakanth Kondabolu, Natalie M Doig, Olaoluwa Ayeko, Bakhtawer Khan, Alexandra Torres, Daniela Calvigioni, Konstantinos Meletis, Tibor Koós, Peter J Magill

Open access · goldAbstract read
In one paragraph

Article in eNeuro, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Arkypallidal neurons in the external globus pallidus can mediate inhibitory control by altering competition in the striatum.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  4. Article
  5. Article
  6. Deep brain stimulation in the subthalamic nucleus for Parkinson's disease can restore dynamics of striatal networks.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 4 countries.

Krishnakanth KondaboluCenter for Molecular and Behavioral Neuroscience, Rutgers University, Newark, NJ 07102.
Natalie M DoigMedical Research Council Brain Network Dynamics Unit, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford OX1 3TH, United Kingdom.ORCID 0000-0001-6821-0264
Olaoluwa AyekoMedical Research Council Brain Network Dynamics Unit, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford OX1 3TH, United Kingdom.
Bakhtawer KhanCenter for Molecular and Behavioral Neuroscience, Rutgers University, Newark, NJ 07102.
Alexandra TorresCenter for Molecular and Behavioral Neuroscience, Rutgers University, Newark, NJ 07102.
Daniela CalvigioniDepartment of Neuroscience, Karolinska Institutet, Stockholm 171 77, Sweden.
Konstantinos MeletisDepartment of Neuroscience, Karolinska Institutet, Stockholm 171 77, Sweden.
Tibor KoósCenter for Molecular and Behavioral Neuroscience, Rutgers University, Newark, NJ 07102 peter.magill@ndcn.ox.ac.uk koostib@gmail.com.
Peter J MagillMedical Research Council Brain Network Dynamics Unit, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford OX1 3TH, United Kingdom peter.magill@ndcn.ox.ac.uk koostib@gmail.com.
Rutgers, The State University of New Jersey · USUniversity of Oxford · GBKarolinska Institutet · SE

Funding

Medical Research Council MC_UU_00003/5Medical Research Council MC_UU_12024/2Wellcome TrustWellcome Trust 101821
6 · The paper itself

Abstract

The striatum and subthalamic nucleus (STN) are considered to be the primary input nuclei of the basal ganglia. Projection neurons of both striatum and STN can extensively interact with other basal ganglia nuclei, and there is growing anatomic evidence of direct axonal connections from the STN to striatum. There remains, however, a pressing need to elucidate the organization and impact of these subthalamostriatal projections in the context of the diverse cell types constituting the striatum. To address this, we conducted monosynaptic retrograde tracing from genetically-defined populations of dorsal striatal neurons in adult male and female mice, quantifying the connectivity from STN neurons to spiny projection neurons, GABAergic interneurons, and cholinergic interneurons. In parallel, we used a combination of

Indexed as

Subthalamic NucleusAnimalsCorpus StriatumFemaleInterneuronsMaleMiceNeuronsParvalbuminsParvalbuminsanatomybasal gangliaelectrophysiologystriatumsubthalamic nucleus

Identifiers

PMID37364998
PMCPMC10327533
OpenAlexW4382139050

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.