Evidence map›Paper›PMID 37364232›Full record

ArticleJCO precision oncology2023

Case of a Patient With Pancreatic Cancer With Sporadic Microsatellite Instability Associated With a

Kathrin Heinrich, Laura E Fischer, Enrico N De Toni, Daniel Markwardt, Daniel Roessler, Georg Beyer, Michael Günther, Steffen Ormanns, Frederick Klauschen, Wolfgang G Kunz and 4 more

Erratum issuedAbstract readCase Reports
In one paragraph

Article in JCO precision oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Fusion genes in pancreatic tumors.Trends in cancer · 2024
    Review
  4. [Research Progress of BRAF Fusion in Non-small Cell Lung Cancer].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2023
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Kathrin HeinrichDepartment of Medicine III and Comprehensive Cancer Centre (CCC), LMU University Hospital Munich, Munich, Germany.ORCID 0000-0003-3580-2313
Laura E FischerDepartment of Medicine III and Comprehensive Cancer Centre (CCC), LMU University Hospital Munich, Munich, Germany.
Enrico N De ToniDepartment of Medicine II and Comprehensive Cancer Centre (CCC), LMU University Hospital Munich, Munich, Germany.
Daniel MarkwardtDepartment of Medicine II and Comprehensive Cancer Centre (CCC), LMU University Hospital Munich, Munich, Germany.
Daniel RoesslerDepartment of Medicine II and Comprehensive Cancer Centre (CCC), LMU University Hospital Munich, Munich, Germany.
Georg BeyerDepartment of Medicine II and Comprehensive Cancer Centre (CCC), LMU University Hospital Munich, Munich, Germany.
Michael GüntherInstitute of Pathology, Ludwig Maximilians University (LMU), Munich, Germany.ORCID 0009-0001-5091-5060
Steffen OrmannsInstitute of Pathology, Ludwig Maximilians University (LMU), Munich, Germany.ORCID 0000-0002-0754-9034
Frederick KlauschenGerman Cancer Consortium (DKTK), Partner Site Munich, Munich, Germany.ORCID 0000-0002-9131-2389
Wolfgang G KunzDepartment of Radiology and Comprehensive Cancer Center (CCC Munich LMU), University Hospital, LMU Munich, Munich, Germany.ORCID 0000-0002-5021-1952
Stefan FröhlingDepartment of Translational Medical Oncology, National Center for Tumor Diseases (NCT) and German Cancer Research Center (DKTZ), Heidelberg, Germany.ORCID 0000-0001-7907-4595
Tilman BrummerInstitute of Molecular Medicine, ZBMZ, Faculty of Medicine, University of Freiburg, Freiburg, Germany.ORCID 0000-0003-4387-7905
Volker HeinemannDepartment of Medicine III and Comprehensive Cancer Centre (CCC), LMU University Hospital Munich, Munich, Germany.ORCID 0000-0002-1349-3321
C Benedikt WestphalenDepartment of Medicine III and Comprehensive Cancer Centre (CCC), LMU University Hospital Munich, Munich, Germany.ORCID 0000-0002-5310-3754

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this case report, we discuss a case of pancreatic cancer bearing a BRAF fusion, leading to MAPK activation, MLHph, and finally MSI.

Indexed as

Colorectal NeoplasmsPancreatic NeoplasmsHumansImmunotherapyMicrosatellite InstabilityProto-Oncogene Proteins B-rafBRAF protein, humanProto-Oncogene Proteins B-raf

Identifiers

PMID37364232
PMCPMC10309529

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.