Evidence map›Paper›PMID 37364156›Full record

ArticleArchives of endocrinology and metabolism2023

Neoadjuvant therapy with anlotinib in a locally advanced and pulmonary metastasis PTC patient harboring TERT promoter and BRAF

Yan-Jun Su, Shao-Hao Cheng, Jun Qian, Ming Zhang, Wen Liu, Xiang-Xiang Zhan, Zhu-Quan Wang, Hai-Dan Liu, Xing-Wei Zhong, Ruo-Chuan Cheng

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Archives of endocrinology and metabolism, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Yan-Jun Su *Department of Thyroid Surgery, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, P.R. China.
Shao-Hao Cheng *Department of Thyroid Surgery, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, P.R. China.
Jun QianDepartment of Thyroid Surgery, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, P.R. China.
Ming ZhangDepartment of Thyroid Surgery, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, P.R. China.
Wen LiuDepartment of Thyroid Surgery, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, P.R. China.
Xiang-Xiang ZhanDepartment of Thyroid Surgery, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, P.R. China.
Zhu-Quan WangDepartment of General Surgery, The First People's Hospital of Honghe State, Mengzi, PR. China.
Hai-Dan LiuDepartment of General Surgery, The First People's Hospital of Honghe State, Mengzi, PR. China.
Xing-Wei ZhongDepartment of General Surgery, The First People's Hospital of Honghe State, Mengzi, PR. China, 13988002917@163.com.
Ruo-Chuan ChengDepartment of Thyroid Surgery, The First Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, P.R. China, ruochuan@foxmail.com.
Kunming Medical University · CNHonghe University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 71-year-old woman with recurrent papillary thyroid carcinoma (PTC) was referred to our hospital. A computed tomography scan revealed extensive recurrence in the neck, invading sternocleidomastoid muscle, internal jugular vein, sternal end of the clavicle, strap muscle and skin; and lateral compartment and subclavian lymph nodes were also involved. Multiple pulmonary micrometastases also noticed. The tumor was considered unresectable; however, the patient was unwilling to accept highly invasive surgery. Therefore, we initiated neoadjuvant therapy with anlotinib, 12mg p.o. daily with a 2-week on/1-week off regimen. The tumor shrunk to resectable state after 4 cycles of treatment, and after 3 weeks of withdrawal, successful surgical resection without gross tumor residual was performed. Pathology confirmed as classic PTC harboring coexistent TERT promoter and BRAF

Indexed as

Carcinoma, PapillaryTelomeraseThyroid NeoplasmsAgedFemaleHumansIndolesIodine RadioisotopesMutationNeoadjuvant TherapyNeoplasm Recurrence, LocalProto-Oncogene Proteins B-rafQuinolinesThyroid Cancer, PapillaryanlotinibBRAF protein, humanIndolesIodine RadioisotopesProto-Oncogene Proteins B-rafQuinolinesTelomeraseTERT protein, human

Identifiers

PMID37364156
PMCPMC10660997
OpenAlexW4382140694

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.