Evidence map›Paper›PMID 37363727›Full record

ReviewFrontiers in cell and developmental biology2023

Glycogen synthase kinase 3β (GSK3β) and presenilin (PS) are key regulators of kinesin-1-mediated cargo motility within axons.

Rupkatha Banerjee, Shermali Gunawardena

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cell and developmental biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Rupkatha BanerjeeDepartment of Neuroscience, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, Jupiter, FL, United States.
Shermali GunawardenaDepartment of Biological Sciences, The State University of New York at Buffalo, Buffalo, NY, United States.
The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & TechnologyUniversity at Buffalo, State University of New York · US

Funding

Dissecting the in vivo role of glycogen synthase kinase-3 beta (GSK3b) in the function of kinesin-1 using CRISPR/cas-1R03NS114731 · NINDS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI GUNAWARDENA, SHERMALI · 2020 to 2020
$157k
A synthetic vesicle to carry modifier compounds to axonal blocks induced by pathogenic polyQR03NS092024 · NINDS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI GUNAWARDENA, SHERMALI · 2015 to 2016
$156k
Dissecting the in vivo role of Huntingtin in Rab vesicle movement on microtubulesR03NS084386 · NINDS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI GUNAWARDENA, SHERMALI · 2013 to 2014
$155k
NINDS NIH HHS R03 NS084386NINDS NIH HHS R03 NS092024NINDS NIH HHS R03 NS114731
6 · The paper itself

Abstract

It has been a quarter century since the discovery that molecular motors are phosphorylated, but fundamental questions still remain as to how specific kinases contribute to particular motor functions, particularly

Indexed as

axonal transportGSK3βkinesin-1phosphorylationpresenilin

Identifiers

PMID37363727
PMCPMC10288942
OpenAlexW4380082806

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.