Evidence map›Paper›PMID 37363411›Full record

ArticleGEN biotechnology2023

Bioorthogonal Stimulated Raman Scattering Imaging Uncovers Lipid Metabolic Dynamics in

Yajuan Li, Phyllis Chang, Shriya Sankaran, Hongje Jang, Yuhang Nie, Audrey Zeng, Sahran Hussain, Jane Y Wu, Xu Chen, Lingyan Shi

Open access · hybridAbstract read
In one paragraph

Article in GEN biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Raman imaging of molecular groups in the wavenumber silent region.Analytical and bioanalytical chemistry · 2026
    Review
  4. Imaging Cellular Metabolic Rewiring with SuMMIT-SRS.bioRxiv : the preprint server for biology · 2025
    Article
  5. Review
  6. Multimodal Optical Imaging Platform for Studying Cellular Metabolism.Journal of visualized experiments : JoVE · 2025
    Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Yajuan LiDepartment of Bioengineering, University of California San Diego, La Jolla, California, USA.
Phyllis ChangDepartment of Bioengineering, University of California San Diego, La Jolla, California, USA.
Shriya SankaranDepartment of Bioengineering, University of California San Diego, La Jolla, California, USA.
Hongje JangDepartment of Bioengineering, University of California San Diego, La Jolla, California, USA.
Yuhang NieDepartment of Neurosciences, School of Medicine, University of California San Diego, La Jolla, California, USA.
Audrey ZengDepartment of Bioengineering, University of California San Diego, La Jolla, California, USA.
Sahran HussainDepartment of Bioengineering, University of California San Diego, La Jolla, California, USA.
Jane Y WuDepartment of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Xu ChenDepartment of Neurosciences, School of Medicine, University of California San Diego, La Jolla, California, USA.
Lingyan ShiDepartment of Bioengineering, University of California San Diego, La Jolla, California, USA.ORCID https://orcid.org/0000-0003-1373-3206
University of California San Diego · USNorthwestern University · US

Funding

Mechanisms by which the ketone body β-hydroxybutyrate counteracts tau pathogenesisR01AG074273 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Xu Chen · 2022 to 2026
$2.7M
Novel Optical Imaging Approach to Study Neurovascular Coupling SystemR21NS125395 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SHI, LINGYAN · 2022 to 2022
$435k
NIA NIH HHS R01 AG074273NINDS NIH HHS R21 NS125395
6 · The paper itself

Abstract

Studies have shown that brain lipid metabolism is associated with biological aging and influenced by dietary and genetic manipulations; however, the underlying mechanisms are elusive. High-resolution imaging techniques propose a novel and potent approach to understanding lipid metabolic dynamics

Identifiers

PMID37363411
PMCPMC10286263
OpenAlexW4381248518

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.