Evidence map›Paper›PMID 37363319›Full record

ArticleFrontiers in molecular neuroscience2023

Detection of Arc/Arg3.1 oligomers in rat brain: constitutive and synaptic activity-evoked dimer expression

Tadiwos F Mergiya, Jens Edvard Trygstad Gundersen, Tambudzai Kanhema, Grant Brighter, Yuta Ishizuka, Clive R Bramham

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Nanoscale Spatial Organization of ARC High- and Low-Order Assemblies at Excitatory Synapses.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Review
  3. "Arc - A viral vector of memory and synaptic plasticity".Current opinion in neurobiology · 2025
    Review
  4. Article
  5. Review
  6. Analysis of Arc/Arg3.1 Oligomerization In Vitro and in Living Cells.International journal of molecular sciences · 2024
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Tadiwos F MergiyaDepartment of Biomedicine, University of Bergen, Bergen, Norway.
Jens Edvard Trygstad GundersenDepartment of Biomedicine, University of Bergen, Bergen, Norway.
Tambudzai KanhemaDepartment of Biomedicine, University of Bergen, Bergen, Norway.
Grant BrighterDepartment of Biomedicine, University of Bergen, Bergen, Norway.
Yuta IshizukaDepartment of Biomedicine, University of Bergen, Bergen, Norway.
Clive R BramhamDepartment of Biomedicine, University of Bergen, Bergen, Norway.
University of Bergen · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The immediate early gene product activity-regulated cytoskeleton-associated protein (Arc or Arg3.1) is a major regulator of long-term synaptic plasticity with critical roles in postnatal cortical development and memory formation. However, the molecular basis of Arc function is undefined. Arc is a hub protein with interaction partners in the postsynaptic neuronal compartment and nucleus. Previous

Indexed as

Activity-regulated cytoskeleton-associated protein (Arc/Arg3.1)brain-derived neurotrophic factor (BDNF)dentate gyrusin situ protein crosslinkinglong-term potentiation (LTP)neuronal cell culturesprotein oligomerizationsynaptic plasticity

Identifiers

PMID37363319
PMCPMC10289200
OpenAlexW4380090314

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.