Evidence map›Paper›PMID 37362091›Full record

ArticleInternational journal of reproductive biomedicine2023

Effects of radioiodine therapy on fertility indicators among men with differentiated thyroid cancer: A cohort study.

Salman Soltani, Atena Aghaee, Seyed Rasoul Zakavi, Mahdi Mottaghi, Maryam Emadzadeh, Soheil Kasaeian Naeini

Open access · goldAbstract read
In one paragraph

Article in International journal of reproductive biomedicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Salman SoltaniKidney Transplantation Complications Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Atena AghaeeNuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Seyed Rasoul ZakaviNuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Mahdi MottaghiKidney Transplantation Complications Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Maryam EmadzadehClinical Research Development Unit, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.
Soheil Kasaeian NaeiniKidney Transplantation Complications Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.ORCID https://orcid.org/0000-0002-8102-3532
Mashhad University of Medical Sciences · IRGhaem Hospital · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Following thyroidectomy, radioiodine therapy is the standard management of differentiated thyroid cancer. The effects of such treatment on testicular function remained a concern for cases and clinicians. Objective: We aimed to observe changes in fertility indicators in men treated with ablation. Materials and Methods: In this prospective cohort study, 18 men with differentiated thyroid cancer from June to December 2020 underwent thyroidectomy plus radioiodine therapy. Participants were grouped based on iodine dose (8 men with 30 mCi vs. 10 men with Results: The mean age of participants was 35.61 Conclusion: Our research showed that even less than 5 GBq irradiation could induce a transient testicular dysfunction in the first 3 months of therapy, but it was mostly reversible after 12 months.

Indexed as

Follicle-stimulating hormoneIodine-131Male infertilitySemen analyses.

Identifiers

PMID37362091
PMCPMC10285192
OpenAlexW4380366334

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.