Evidence map›Paper›PMID 37361869›Full record

ReviewAdvances in laboratory medicine2022

Impact of SARS-CoV-2 infection on liver disease.

Sergio Salgüero Fernández, Pablo Gabriel Medina, Alejandro Almería Lafuente, María Antonieta Ballesteros Vizoso, Angielys Zamora Trillo, Gregori Casals Mercadal, Gemma Solé Enrech, Marta Lalana Garcés, Armando R Guerra Ruiz, Oihana Ortiz Pastor and 1 more

Open access · diamondAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Advances in laboratory medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Sergio Salgüero FernándezBiochemistry of Liver Disease Commision-Spanish Society of Laboratory Medicine (SEQC-ML), Alcorcon, Spain.
Pablo Gabriel MedinaBiochemistry of Liver Disease Commision-Spanish Society of Laboratory Medicine (SEQC-ML), Alcorcon, Spain.ORCID https://orcid.org/0000-0001-8896-8611
Alejandro Almería LafuenteBiochemistry of Liver Disease Commision-Spanish Society of Laboratory Medicine (SEQC-ML), Alcorcon, Spain.
María Antonieta Ballesteros VizosoBiochemistry of Liver Disease Commision-Spanish Society of Laboratory Medicine (SEQC-ML), Alcorcon, Spain.
Angielys Zamora TrilloBiochemistry of Liver Disease Commision-Spanish Society of Laboratory Medicine (SEQC-ML), Alcorcon, Spain.
Gregori Casals MercadalBiochemistry of Liver Disease Commision-Spanish Society of Laboratory Medicine (SEQC-ML), Alcorcon, Spain.
Gemma Solé EnrechBiochemistry of Liver Disease Commision-Spanish Society of Laboratory Medicine (SEQC-ML), Alcorcon, Spain.
Marta Lalana GarcésBiochemistry of Liver Disease Commision-Spanish Society of Laboratory Medicine (SEQC-ML), Alcorcon, Spain.
Armando R Guerra RuizBiochemistry of Liver Disease Commision-Spanish Society of Laboratory Medicine (SEQC-ML), Alcorcon, Spain.
Oihana Ortiz PastorBiochemistry of Liver Disease Commision-Spanish Society of Laboratory Medicine (SEQC-ML), Alcorcon, Spain.
Manuel Morales RuizBiochemistry of Liver Disease Commision-Spanish Society of Laboratory Medicine (SEQC-ML), Alcorcon, Spain.
Spanish Society of Family and Community Medicine · ESCentro de Salud Casa del Barco · ESHospital General Universitario Gregorio Marañón · ESHospital Royo Villanova · ESHospital Universitario Fundación Alcorcón · ESMarqués de Valdecilla University Hospital · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Abnormal liver biochemistry is not a rare finding in the context of SARS-CoV-2 infection, regardless of patients having pre-existing chronic disease or not. Content: This review examines the current body of knowledge on the relationship between COVID-19 and liver injury, which is frequently found in this setting. Summary: Although the pathogenesis of liver injury is not fully understood, it has been suggested to be the result of a combination of multiple factors. These include direct injury caused by the virus, immune system hyperactivation, ischemic and drug-induced injury. The prognostic valor of these alterations is also the subject of intense research. Due to their potential impact, these alterations require proper management and treatment, especially in patients with chronic liver disease or liver transplant recipients. Outlook: Some aspects associated with liver injury during COVID-19, especially in severe presentations, are not well understood. Studies assessing the clinical impact of COVID-19 on the healthy or diseased liver may help adjust treatment and immunization guidelines to the profile of the patient.

Indexed as

liver injurytransaminasevirus

Identifiers

PMID37361869
PMCPMC10197317
OpenAlexW4281738932

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.