Evidence map›Paper›PMID 37361157›Full record

ArticleFrontiers in public health2023

Effect of the "universal test and treat" policy on the characteristics of persons registering for HIV care and initiating antiretroviral therapy in Uganda.

Levicatus Mugenyi, Christian H Hansen, Philippe Mayaud, Janet Seeley, Robert Newton, Mastula Nanfuka, Andrew Abaasa, Kenneth Mugisha, Michael Etukoit, Pontiano Kaleebu and 1 more

Abstract read
In one paragraph

Article in Frontiers in public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
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  4. Review
  5. Article
  6. Article
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  8. Article
  9. Article
  10. Article
  11. Varied Immunological Response to Test and Treat with Antiretroviral Therapy: A Longitudinal Study with Mixed Model Analysis.Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Levicatus MugenyiMRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.
Christian H HansenMRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.
Philippe MayaudMRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.
Janet SeeleyMRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.
Robert NewtonMRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.
Mastula NanfukaThe AIDS Support Organization, Kampala, Uganda.
Andrew AbaasaMRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.
Kenneth MugishaThe AIDS Support Organization, Kampala, Uganda.
Michael EtukoitThe AIDS Support Organization, Kampala, Uganda.
Pontiano KaleebuMRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.
Eugene RuzagiraMRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.

Funding

Medical Research Council MC_UU_00027/3Medical Research Council MC_UU_00027/5Medical Research Council MC_UU_00033/1Medical Research Council MR/K019708/1Medical Research Council MR/R010161/1
6 · The paper itself

Abstract

We examined the effect of the Universal Test and Treat (UTT) policy on the characteristics of people living with HIV (PLHIV) at enrolment in HIV care and initiation of antiretroviral therapy (ART) in Uganda using data from 11 nationally representative clinics of The AIDS Support Organisation (TASO). We created two retrospective PLHIV cohorts: pre-UTT (2004-2016), where ART initiation was conditional on CD4 cell count and UTT (2017-2022), where ART was initiated regardless of World Health Organisation (WHO) clinical stage or CD4 cell count. We used a two-sample test of proportions and Wilcoxon rank-sum test to compare proportions and medians, respectively, between the cohorts. A total of 244,693 PLHIV were enrolled at the clinics [pre-UTT, 210,251 (85.9%); UTT, 34,442 (14.1%)]. Compared to the pre-UTT cohort, the UTT cohort had higher proportions of PLHIV that were male (

Indexed as

Anti-HIV AgentsHIV InfectionsAgedFemaleHumansMalePolicyRetrospective StudiesUgandaAnti-HIV Agentsantiretroviral therapyHIV/AIDSTASOUgandauniversal test and treat

Identifiers

PMID37361157
PMCPMC10289544

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.