ArticleKidney international reports2023
Association of Country Income Level With the Characteristics and Outcomes of Critically Ill Patients Hospitalized With Acute Kidney Injury and COVID-19.
Article in Kidney international reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.
- Health inequalities and outcomes following acute kidney injury: a systematic review & meta-analyses of observational studies.BMC nephrology · 2025Pooled it
- Global geographic and socioeconomic disparities in COVID-associated acute kidney injury: a systematic review and meta-analysis.Journal of global health · 2025Pooled it
- The impact of social determinants of health on acute kidney injury.Nature reviews. Nephrology · 2026Review
- The global epidemiology of acute kidney injury: challenges and opportunities.Nature reviews. Nephrology · 2026Review
- Long-term kidney outcomes after COVID-19: a matched cohort study using the OpenSAFELY platform.The Lancet regional health. Europe · 2025Article
- Acute kidney injury in the pandemic years revisited: distinct patterns of staging and recovery in patients with and without COVID-19.Journal of nephrology · 2025Article
- Omicron surge impact on acute kidney injury in ICU patients: A study using the ISARIC COVID-19 database.PloS one · 2025Observational
- Kidney damage associated with COVID-19: from the acute to the chronic phase.Renal failure · 2024Review
- Outcome and Determining Characteristics of ICU Patients with Acute Kidney Injury in a Low-Income Country, a Multicenter Experience.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2024Article
- Infections and Acute Kidney Injury: A Global Perspective.Seminars in nephrology · 2023Review
- Acute kidney injury and COVID-19 in Brazil: disparities in outcomes between public and private hospitals in Rio de Janeiro reveal issues of equity in intensive care.Jornal brasileiro de nefrologiaArticle
- Same disease, different outcomes: a retrospective cohort study of COVID-19-associated AKI across Brazil's dual-tiered healthcare system.Jornal brasileiro de nefrologiaArticle
Corrections and comments
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Authors and funding
13 authors at 7 institutions in 4 countries.
Funding
Abstract
Introduction: Acute kidney injury (AKI) has been identified as one of the most common and significant problems in hospitalized patients with COVID-19. However, studies examining the relationship between COVID-19 and AKI in low- and low-middle income countries (LLMIC) are lacking. Given that AKI is known to carry a higher mortality rate in these countries, it is important to understand differences in this population. Methods: This prospective, observational study examines the AKI incidence and characteristics of 32,210 patients with COVID-19 from 49 countries across all income levels who were admitted to an intensive care unit during their hospital stay. Results: Among patients with COVID-19 admitted to the intensive care unit, AKI incidence was highest in patients in LLMIC, followed by patients in upper-middle income countries (UMIC) and high-income countries (HIC) (53%, 38%, and 30%, respectively), whereas dialysis rates were lowest among patients with AKI from LLMIC and highest among those from HIC (27% vs. 45%). Patients with AKI in LLMIC had the largest proportion of community-acquired AKI (CA-AKI) and highest rate of in-hospital death (79% vs. 54% in HIC and 66% in UMIC). The association between AKI, being from LLMIC and in-hospital death persisted even after adjusting for disease severity. Conclusions: AKI is a particularly devastating complication of COVID-19 among patients from poorer nations where the gaps in accessibility and quality of healthcare delivery have a major impact on patient outcomes.
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Registered trials
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