Evidence map›Paper›PMID 37360040›Full record

ReviewACS measurement science au2023

Potential Avenues for Exosomal Isolation and Detection Methods to Enhance Small-Cell Lung Cancer Analysis.

Waqar Ahmed Afridi, Simon Strachan, Surasak Kasetsirikul, Amandeep Singh Pannu, Narshone Soda, Daniel Gough, Nam-Trung Nguyen, Muhammad J A Shiddiky

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in ACS measurement science au, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Current trends in exosomes as therapeutic drug delivery systems.Naunyn-Schmiedeberg's archives of pharmacology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Waqar Ahmed AfridiSchool of Environment and Science, Griffith University, Nathan Campus, Nathan, QLD 4111, Australia.
Simon StrachanSchool of Environment and Science, Griffith University, Nathan Campus, Nathan, QLD 4111, Australia.
Surasak KasetsirikulQueensland Micro and Nanotechnology Centre, Griffith University, Nathan Campus, Nathan, QLD 4111, Australia.
Amandeep Singh PannuQueensland Micro and Nanotechnology Centre, Griffith University, Nathan Campus, Nathan, QLD 4111, Australia.
Narshone SodaQueensland Micro and Nanotechnology Centre, Griffith University, Nathan Campus, Nathan, QLD 4111, Australia.
Daniel GoughCentre for Cancer Research, Hudson Institute of Medical Research, Clayton, Vic 3168, Australia.
Nam-Trung NguyenQueensland Micro and Nanotechnology Centre, Griffith University, Nathan Campus, Nathan, QLD 4111, Australia.
Muhammad J A ShiddikySchool of Environment and Science, Griffith University, Nathan Campus, Nathan, QLD 4111, Australia.ORCID https://orcid.org/0000-0003-4526-4109
Griffith University · AUHudson Institute of Medical Research · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Around the world, lung cancer has long been the main factor in cancer-related deaths, with small-cell lung cancer (SCLC) being the deadliest form of lung cancer. Cancer cell-derived exosomes and exosomal miRNAs are considered promising biomarkers for diagnosing and prognosis of various diseases, including SCLC. Due to the rapidity of SCLC metastasis, early detection and diagnosis can offer better diagnosis and prognosis and therefore increase the patient's chances of survival. Over the past several years, many methodologies have been developed for analyzing non-SCLC-derived exosomes. However, minimal advances have been made in SCLC-derived exosome analysis methodologies. This Review discusses the epidemiology and prominent biomarkers of SCLC. Followed by a discussion about the effective strategies for isolating and detecting SCLC-derived exosomes and exosomal miRNA, highlighting the critical challenges and limitations of current methodologies. Finally, an overview is provided detailing future perspectives for exosome-based SCLC research.

Identifiers

PMID37360040
PMCPMC10288614
OpenAlexW4320725824

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.