ArticleJAMIA open2023
Research data warehouse: using electronic health records to conduct population-based observational studies.
Article in JAMIA open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Resource Utilization and Timeliness of Care in Patients With Incidentally Detected Lung Nodules.CHEST pulmonary · 2026Article
- Asthma Burden in Mild Adult Asthma in the PEARL Survey: Asthma Control and Health Status.The journal of allergy and clinical immunology. In practice · 2026Article
- Drivers of disparities in asthma exacerbation and healthcare utilization: a quantitative analysis of neighborhood deprivation in Southern California, United States.Preventive medicine reports · 2026Article
- A generative approach for semantic auditing of electronic health records.NPJ digital medicine · 2026Article
- Do Rural-Urban Disparities Translate into Nursing Complexity at Hospital Admission? Evidence from a Single Tertiary-Care Pediatric Hospital in Italy.Children (Basel, Switzerland) · 2026Article
- Symptom patterns before and after indolent systemic mastocytosis: A matched cohort analysis.The journal of allergy and clinical immunology. Global · 2026Article
- Recombinant zoster vaccine is associated with a reduced risk of dementia.Nature communications · 2026Article
- The AIR·MS data platform for artificial intelligence in healthcare.JAMIA open · 2025Article
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- Symptoms of Asthma Extracted Through Natural Language Processing and Their Associations With Acute Asthma Exacerbation in Adults With Mild Asthma.The journal of allergy and clinical immunology. In practice · 2025Article
- Fracture risk by cortisol excess status in patients with adrenal incidentalomas: a population-based cohort study.JBMR plus · 2025Article
- Impact of the Advent of CollagenaseThe Permanente journal · 2025Article
- Trends in Postpartum Depression by Race, Ethnicity, and Prepregnancy Body Mass Index.JAMA network open · 2024Article
- Machine Learning on 50,000 Manuscripts Shows Increased Clinical Research by Academic Cardiac Surgeons.The Journal of surgical research · 2024Article
- Neighborhood Deprivation and Crime on Asthma Exacerbations and Utilization in Mild Adult Asthma.The journal of allergy and clinical immunology. In practice · 2024Article
- MASTering systemic mastocytosis: Lessons learned from a large patient cohort.The journal of allergy and clinical immunology. Global · 2024Article
- Telemedicine Compared to Office-Based Care of Patients With Cardiac Symptoms: Treatment and Outcomes.JACC. Advances · 2024Article
- Risk Factors for Acute Asthma Exacerbations in Adults With Mild Asthma.The journal of allergy and clinical immunology. In practice · 2024Article
- Racial and Ethnic Differences in the Prevalence of Severe Aortic Stenosis by Echocardiography.The Permanente journal · 2024Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Electronic health records and many legacy systems contain rich longitudinal data that can be used for research; however, they typically are not readily available. Materials and methods: At Kaiser Permanente Southern California (KPSC), a research data warehouse (RDW) has been developed and maintained since the late 1990s and widely extended in 2006, aggregating and standardizing data collected from internal and a few external sources. This article provides a high-level overview of the RDW and discusses challenges common to data warehouses or repositories for research use. To demonstrate the application of the data, we report the volume, patient characteristics, and age-adjusted prevalence of selected medical conditions and utilization rates of selected medical procedures. Results: A total of 105 million person-years of health plan enrollment was recorded in the RDW between 1981 and 2018, with most healthcare utilization data available since early or middle 1990s. Among active enrollees on December 31, 2018, 15% were ≥65 years of age, 33.9% were non-Hispanic white, 43.3% Hispanic, 11.0% Asian, and 8.4% African American, and 34.4% of children (2-17 years old) and 72.1% of adults (≥18 years old) were overweight or obese. The age-adjusted prevalence of asthma, atrial fibrillation, diabetes mellitus, hypercholesteremia, and hypertension increased between 2001 and 2018. Hospitalization and Emergency Department (ED) visit rates appeared lower, and office visit rates seemed higher at KPSC compared to the reported US averages. Discussion and conclusion: Although the RDW is unique to KPSC, its methodologies and experience may provide useful insights for researchers of other healthcare systems worldwide in the era of big data analysis.
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