Evidence map›Paper›PMID 37359898›Full record

ReviewAdvances in laboratory medicine2023

Upregulation of SPINK2 in acute myeloid leukemia.

Sümbül Gezer, Zeliha Emrence, Tuğrul Elverdi, Muhlis Cem Ar, Burcu Salman Yaylaz, Ferda Paçal, Ayşegül Ünüvar, Melda Sarıman, Ahmet Emre Eşkazan, Serap Karaman and 4 more

Open access · diamondAbstract readReview
In one paragraph

Review in Advances in laboratory medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Sümbül GezerDepartment of Genetics, Istanbul University, Aziz Sancar Institute of Experimental Medicine, Istanbul, Türkiye.
Zeliha EmrenceDepartment of Genetics, Istanbul University, Aziz Sancar Institute of Experimental Medicine, Istanbul, Türkiye.
Tuğrul ElverdiDepartment of Internal Medicine, Cerrahpasa Faculty of Medicine, Division of Hematology, Istanbul University-Cerrahpasa, Istanbul, Türkiye.
Muhlis Cem ArDepartment of Internal Medicine, Cerrahpasa Faculty of Medicine, Division of Hematology, Istanbul University-Cerrahpasa, Istanbul, Türkiye.
Burcu Salman YaylazDepartment of Genetics, Istanbul University, Aziz Sancar Institute of Experimental Medicine, Istanbul, Türkiye.
Ferda PaçalDepartment of Genetics, Istanbul University, Aziz Sancar Institute of Experimental Medicine, Istanbul, Türkiye.
Ayşegül ÜnüvarDivision of Pediatric Hematology and Oncology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Türkiye.
Melda SarımanDepartment of Genetics, Istanbul University, Aziz Sancar Institute of Experimental Medicine, Istanbul, Türkiye.
Ahmet Emre EşkazanDepartment of Internal Medicine, Cerrahpasa Faculty of Medicine, Division of Hematology, Istanbul University-Cerrahpasa, Istanbul, Türkiye.ORCID https://orcid.org/0000-0001-9568-0894
Serap KaramanDivision of Pediatric Hematology and Oncology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Türkiye.
Ayşe SalihoğluDepartment of Internal Medicine, Cerrahpasa Faculty of Medicine, Division of Hematology, Istanbul University-Cerrahpasa, Istanbul, Türkiye.
Zeynep KarakaşDivision of Pediatric Hematology and Oncology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Türkiye.
Neslihan AbacıDepartment of Genetics, Istanbul University, Aziz Sancar Institute of Experimental Medicine, Istanbul, Türkiye.
Sema Sırma-EkmekciDepartment of Genetics, Istanbul University, Aziz Sancar Institute of Experimental Medicine, Istanbul, Türkiye.ORCID https://orcid.org/0000-0002-1201-7542
Istanbul University · TRIstanbul University-Cerrahpaşa · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Acute myeloid leukemia (AML) is a highly heterogeneous disease. Although patients can be classified into risk groups based on their genetic changes, the prognosis of disease within these categories varies widely. This situation raises the need to search for new molecular markers related to AML. Serine peptidase inhibitor Kazal type 2 ( Methods: We analyzed Results: We found that the expression of Conclusions: Our results suggest that

Indexed as

acute myeloid leukemiaAMLHUSI-IIserin protease inhibitorsSPINK2

Identifiers

PMID37359898
PMCPMC10197194
OpenAlexW4321015411

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.