Evidence map›Paper›PMID 37359731›Full record

ArticleRegenerative biomaterials2023

An extracellular matrix-mimetic coating with dual bionics for cardiovascular stents.

Nuoya Chen, Mingyu Li, Haoshaung Wu, Yumei Qin, Jian Wang, Kai Xu, Rifang Luo, Li Yang, Yunbing Wang, Xingdong Zhang

Open access · goldAbstract read
In one paragraph

Article in Regenerative biomaterials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Nuoya ChenNational Engineering Research Center for Biomaterials, Sichuan University, Chengdu 610064, China.
Mingyu LiNational Engineering Research Center for Biomaterials, Sichuan University, Chengdu 610064, China.
Haoshaung WuNational Engineering Research Center for Biomaterials, Sichuan University, Chengdu 610064, China.
Yumei QinNational Engineering Research Center for Biomaterials, Sichuan University, Chengdu 610064, China.
Jian WangShanxi Key Laboratory of Functional Proteins, Shanxi Jinbo Bio-Pharmaceutical Co., Ltd, Taiyuan 030032, Shanxi, China.
Kai XuDepartment of Cardiology, General Hospital of Northern Theater Command, Shenyang 110000, China.
Rifang LuoNational Engineering Research Center for Biomaterials, Sichuan University, Chengdu 610064, China.
Li YangNational Engineering Research Center for Biomaterials, Sichuan University, Chengdu 610064, China.
Yunbing WangNational Engineering Research Center for Biomaterials, Sichuan University, Chengdu 610064, China.
Xingdong ZhangNational Engineering Research Center for Biomaterials, Sichuan University, Chengdu 610064, China.
Sichuan University · CNGeneral Hospital of Shenyang Military Region · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anti-inflammation and anti-coagulation are the primary requirements for cardiovascular stents and also the widely accepted trajectory for multi-functional modification. In this work, we proposed an extracellular matrix (ECM)-mimetic coating for cardiovascular stents with the amplified functionalization of recombinant humanized collagen type III (rhCOL III), where the biomimetics were driven by structure mimicry and component/function mimicry. Briefly, the structure-mimic was constructed by the formation of a nanofiber (NF) structure via the polymerization of polysiloxane with a further introduction of amine groups as the nanofibrous layer. The fiber network could function as a three-dimensional reservoir to support the amplified immobilization of rhCoL III. The rhCOL III was tailored for anti-coagulant, anti-inflammatory and endothelialization promotion properties, which endows the ECM-mimetic coating with desired surface functionalities. Stent implantation in the abdominal aorta of rabbits was conducted to validate the

Indexed as

anti-coagulationcardiovascular stentendothelializationextracellular matrixrecombinant humanized collagen type III

Identifiers

PMID37359731
PMCPMC10287914
OpenAlexW4381570390

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.