Evidence map›Paper›PMID 37359374›Full record

ArticleFrontiers in genetics2023

Host genotype affects endotoxin release in excreta of broilers at slaughter age.

F Marcato, J M J Rebel, S K Kar, I M Wouters, D Schokker, A Bossers, F Harders, J W van Riel, M Wolthuis-Fillerup, I C de Jong

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

F MarcatoWageningen Livestock Research, Wageningen University and Research, Wageningen, Netherlands.
J M J RebelWageningen Bioveterinary Research, Lelystad, Netherlands.
S K KarWageningen Livestock Research, Wageningen University and Research, Wageningen, Netherlands.
I M WoutersInstitute for Risk Assessment Sciences, Utrecht University, Utrecht, Netherlands.
D SchokkerWageningen Bioveterinary Research, Lelystad, Netherlands.
A BossersWageningen Bioveterinary Research, Lelystad, Netherlands.
F HardersWageningen Bioveterinary Research, Lelystad, Netherlands.
J W van RielWageningen Livestock Research, Wageningen University and Research, Wageningen, Netherlands.
M Wolthuis-FillerupWageningen Livestock Research, Wageningen University and Research, Wageningen, Netherlands.
I C de JongWageningen Livestock Research, Wageningen University and Research, Wageningen, Netherlands.
Wageningen University & Research · NLUtrecht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Host genotype, early post-hatch feeding, and pre- and probiotics are factors known to modulate the gut microbiome. However, there is a knowledge gap on the effect of both chicken genotype and these dietary strategies and their interplay on fecal microbiome composition and diversity, which, in turn, can affect the release of endotoxins in the excreta of broilers. Endotoxins are a major concern as they can be harmful to both animal and human health. The main goal of the current study was to investigate whether it was possible to modulate the fecal microbiome, thereby reducing endotoxin concentrations in the excreta of broiler chickens. An experiment was carried out with a 2 × 2 × 2 factorial arrangement including the following three factors: 1) genetic strain (fast-growing Ross 308 vs. slower growing Hubbard JA757); 2) no vs. combined use of probiotics and prebiotics in the diet and drinking water; and 3) early feeding at the hatchery vs. non-early feeding. A total of 624 Ross 308 and 624 Hubbard JA757 day-old male broiler chickens were included until d 37 and d 51 of age, respectively. Broilers (

Indexed as

broilerearly feedingendotoxingenetic strainmicrobiomeperformanceprobiotics

Identifiers

PMID37359374
PMCPMC10285083
OpenAlexW4380049455

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.