ArticleAdvances in laboratory medicine2021
Big data and reference intervals: rationale, current practices, harmonization and standardization prerequisites and future perspectives of indirect determination of reference intervals using routine data.
Article in Advances in laboratory medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed.
- Intact Parathyroid Hormone Reference Intervals: Importance of Pre-Processing for Indirect Reference Interval Estimation.Diagnostics (Basel, Switzerland) · 2026Article
- Establishing Thyroid Reference Intervals Through Hierarchical Cluster Analysis: A Comparative Evaluation of Limit Estimation and Partitioning Methods.Journal of clinical medicine · 2026Article
- Reference intervals reimagined with IRIS for earlier detection and better disease monitoring.Scientific reports · 2026Article
- Calculation of reference intervals using an indirect approach from laboratory database.Advances in laboratory medicine · 2026Article
- First trimester of pregnancy TSH laboratory specific reference intervals established by an indirect method.Biochemia medica · 2026Observational
- Big data-driven establishment and bias comparison of serum ferritin reference intervals in Zhejiang Chinese adults using six algorithms.Scientific reports · 2026Article
- Diversity of words and words for diversity.Frontiers in psychiatry · 2026Article
- Practice Variations in Pediatric Hypoglycemia Management: A Survey of Emergency Medicine Physicians.Cureus · 2025Article
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- Data science applied to the assessment of biological variation estimates.Advances in laboratory medicine · 2025Article
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- Optimizing vitamin supplementation via reference interval update of vitamins A, E, B1, and B6 using HPLC.Journal of clinical biochemistry and nutrition · 2025Article
- Calculation of a Reference Interval for Rectal Temperature in Adult Dogs Presenting for Veterinary Care Using an Algorithm for Mixed Data.Animals : an open access journal from MDPI · 2024Article
- The BioRef Infrastructure, a Framework for Real-Time, Federated, Privacy-Preserving, and Personalized Reference Intervals: Design, Development, and Application.Journal of medical Internet research · 2023Article
- Establishment of Reference Intervals for Renal Function Clinical Chemistry Parameters in an Indonesian Tertiary Hospital.Archives of Razi Institute · 2023Article
- Hepatic Coccidiosis in Wild Rabbits in Greece: Parasite Detection on Liver Imprints and the Associated Biochemical Profile.Veterinary sciences · 2023Article
- Indirect Method for Estimation of Reference Intervals of Inflammatory Markers.Annals of laboratory medicine · 2023Article
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- Defining Reference Ranges for Serum Anti-Müllerian Hormone on a Large Cohort of Normozoospermic Adult Men Highlights New Potential Physiological Functions of AMH on FSH Secretion and Sperm Motility.The Journal of clinical endocrinology and metabolism · 2022Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Reference intervals are commonly used as a decision-making tool. In this review, we provide an overview on "big data" and reference intervals, describing the rationale, current practices including statistical methods, essential prerequisites concerning data quality, including harmonization and standardization, and future perspectives of the indirect determination of reference intervals using routine laboratory data.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.