Evidence map›Paper›PMID 37359109›Full record

ArticleJGH open : an open access journal of gastroenterology and hepatology2023

Necessity for surveillance for hepatocellualr carcinoma in older patients with chronic hepatitis C who achieved sustained virological response.

Shun Ishido, Nobuharu Tamaki, Masayuki Kurosaki, Nami Mori, Keiji Tsuji, Chitomi Hasebe, Toshie Mashiba, Hironori Ochi, Yutaka Yasui, Takehiro Akahane and 17 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JGH open : an open access journal of gastroenterology and hepatology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors at 19 institutions in 1 country.

Shun IshidoDepartment of Gastroenterology and Hepatology Musashino Red Cross Hospital Tokyo Japan.ORCID https://orcid.org/0000-0002-7036-5633
Nobuharu TamakiDepartment of Gastroenterology and Hepatology Musashino Red Cross Hospital Tokyo Japan.
Masayuki KurosakiDepartment of Gastroenterology and Hepatology Musashino Red Cross Hospital Tokyo Japan.
Nami MoriDepartment of Gastroenterology Hiroshima Red Cross Hospital and Atomic Bomb Survivors' Hospital Hiroshima Japan.
Keiji TsujiDepartment of Gastroenterology Hiroshima Red Cross Hospital and Atomic Bomb Survivors' Hospital Hiroshima Japan.
Chitomi HasebeDepartment of Gastroenterology Asahikawa Red Cross Hospital Asahikawa Japan.
Toshie MashibaCenter for Liver-Biliary-Pancreatic Disease Matsuyama Red Cross Hospital Matsuyama Japan.
Hironori OchiCenter for Liver-Biliary-Pancreatic Disease Matsuyama Red Cross Hospital Matsuyama Japan.
Yutaka YasuiDepartment of Gastroenterology and Hepatology Musashino Red Cross Hospital Tokyo Japan.
Takehiro AkahaneDepartment of Gastroenterology Ishinomaki Red Cross Hospital Ishinomaki Japan.
Koichiro FurutaDepartment of Gastroenterology Masuda Red Cross Hospital Masuda Japan.
Haruhiko KobashiDepartment of Gastroenterology Japanese Red Cross Okayama Hospital Okayama Japan.
Hideki FujiiDepartment of Gastroenterology Japanese Red Cross Kyoto Daiichi Hospital Kyoto Japan.
Toru IshiiDepartment of Gastroenterology Japanese Red Cross Akita Hospital Akita Japan.
Hiroyuki MarusawaDepartment of Gastroenterology and Hepatology Osaka Red Cross Hospital Osaka Japan.
Masahiko KondoDepartment of Gastroenterology Otsu Red Cross Hospital Otsu Japan.
Atsunori KusakabeDepartment of Gastroenterology Japanese Red Cross Aichi Medical Center Nagoya Daini Hospital Nagoya Japan.
Hideo YoshidaDepartment of Gastroenterology Japanese Red Cross Medical Center Tokyo Japan.
Yasushi UchidaDepartment of Gastroenterology Matsue Red Cross Hospital Matsue Japan.
Toshifumi TadaDepartment of Internal Medicine Himeji Red Cross Hospital Himeji Japan.ORCID https://orcid.org/0000-0002-0976-6761
Shinichiro NakamuraDepartment of Internal Medicine Himeji Red Cross Hospital Himeji Japan.
Akari MitsudaDepartment of Gastroenterology Tottori Red Cross Hospital Tottori Japan.
Chikara OgawaDepartment of Gastroenterology Takamatsu Red Cross Hospital Takamatsu Japan.
Hirotaka AraiDepartment of Gastroenterology Maebashi Red Cross Hospital Maebashi Japan.
Toshimitsu MurohisaDepartment of Gastroenterology Japanese Red Cross Ashikaga Hospital Ashikaga Japan.
Minoru UebayashiDepartment of Gastroenterology Kitami Red Cross Hospital Kitami Japan.
Namiki IzumiDepartment of Gastroenterology and Hepatology Musashino Red Cross Hospital Tokyo Japan.
Musashino Red Cross Hospital · JPHimeji Red Cross Hospital · JPHiroshima Red Cross Hospital & Atomic-bomb Survivors Hospital · JPMatsuyama Red Cross Hospital · JPAkita Red Cross Hospital · JPAshikaga Red Cross Hospital · JPJapanese Red Cross Asahikawa Hospital · JPJapanese Red Cross Hokkaido College of Nursing · JPJapanese Red Cross Medical Center · JPJapanese Red Cross Nagoya Daini Hospital · JPKyoto first Red Cross hospital · JPMaebashi Red Cross Hospital · JPMatsue Red Cross Hospital · JPOkayama Red Cross General Hospital · JPOsaka Red Cross Hospital · JPOtsu Red Cross Hospital · JPTakamatsu Red Cross Hospital · JPTottori Prefectural Central Hospital · JPTsuda University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aim: Hepatocellular carcinoma (HCC) surveillance in low-risk patients (annual incidence <1.5%) is not recommended per the American Association for the Study of Liver Diseases guidelines. Because patients with chronic hepatitis C with non-advanced fibrosis who have achieved sustained virological response (SVR) have a low risk of HCC, HCC surveillance is not recommended for them. However, aging is a risk factor for HCC; threfore, the necessity for HCC surveillance in older patients with non-advanced fibrosis needs to be verified. Methods: This multicenter, prospective study enrolled 4993 patients with SVR (1998 patients with advanced fibrosis and 2995 patients with non-advanced fibrosis). The HCC incidence was examined with particular attention to age. Results: The 3-year incidence of HCC in patients with advanced and non-advanced fibrosis was 9.2% (95% CI: 7.8-10.9) and 2.9% (95% CI: 2.1-3.7), respectively. HCC incidence was significantly higher in patients with advanced fibrosis ( Conclusions: Male patients with non-advanced fibrosis aged ≥60 years have a higher risk of developing HCC and, thus, require HCC surveillance.

Indexed as

chronic hepatitis Chepatocellular carcinomasurveillancesustained virological response

Identifiers

PMID37359109
PMCPMC10290273
OpenAlexW4379529006

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.