Evidence map›Paper›PMID 37358811›Full record

ArticleApplied microbiology and biotechnology2023

Evolutionary relevance of metabolite production in relation to marine sponge bacteria symbiont.

Alshaimaa M Hamoda, Rania Hamdy, Bahgat Fayed, Mohamed Abouleish, Ashna Sulaiman, Mohamad Hamad, Sameh S M Soliman

Abstract read
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In one paragraph

Article in Applied microbiology and biotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Alshaimaa M Hamoda *Research Institute for Medical and Health Sciences, University of Sharjah, P.O. Box 27272, Sharjah, UAE.
Rania Hamdy *Research Institute for Medical and Health Sciences, University of Sharjah, P.O. Box 27272, Sharjah, UAE.
Bahgat FayedResearch Institute for Medical and Health Sciences, University of Sharjah, P.O. Box 27272, Sharjah, UAE.
Mohamed AbouleishDepartment of Biology, Chemistry and Environmental Sciences, College of Arts and Sciences, American University of Sharjah, P.O. Box 26666, Sharjah, UAE.
Ashna SulaimanResearch Institute for Medical and Health Sciences, University of Sharjah, P.O. Box 27272, Sharjah, UAE.
Mohamad HamadResearch Institute for Medical and Health Sciences, University of Sharjah, P.O. Box 27272, Sharjah, UAE.
Sameh S M SolimanResearch Institute for Medical and Health Sciences, University of Sharjah, P.O. Box 27272, Sharjah, UAE. ssoliman@sharjah.ac.ae.ORCID http://orcid.org/0000-0002-7691-615X
University of Sharjah · AEAmerican University of Sharjah · AEZagazig University · EG

Funding

University of Sharjah ‎2301110176‎
6 · The paper itself

Abstract

Sponges are habitats for a diverse community of microorganisms. Sponges provide shelter, whereas microbes provide a complementary defensive mechanism. Here, a symbiotic bacterium, identified as Bacillus spp., was isolated from a marine sponge following culture enrichment. Fermentation-assisted metabolomics using thin-layer chromatography (TLC) and gas chromatography-mass spectrometry (GC-MS) indicated that marine simulated nutrition and temperature was the optimum in metabolite production represented by the highest number of metabolites and the diverse chemical classes when compared to other culture media. Following large-scale culture in potato dextrose broth (PDB) and dereplication, compound M1 was isolated and identified as octadecyl-1-(2',6'-di-tert-butyl-1'-hydroxyphenyl) propionate. M1, at screening concentrations up to 10 mg/ml, showed no activity against prokaryotic bacteria including Staphylococcus aureus and Escherichia coli, while 1 mg/ml of M1 was sufficient to cause a significant killing effect on eukaryotic cells including Candida albicans, Candida auris, and Rhizopus delemar fungi and different mammalian cells. M1 exhibited MIC

Indexed as

BacillusPoriferaAnimalsAntifungal AgentsBacteriaBiological EvolutionCandida albicansMammalsAntifungal AgentsAntifungal activityDefensive metaboliteMarine spongeSymbiont bacteria

Identifiers

PMID37358811
OpenAlexW4382010795

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.