Evidence map›Paper›PMID 37358467›Full record

ArticleJournal of medicinal chemistry2023

Synthesis of a Novel Boronic Acid Transition State Inhibitor, MB076: A Heterocyclic Triazole Effectively Inhibits

Rachel A Powers, Cynthia M June, Micah C Fernando, Erin R Fish, Olivia L Maurer, Rachelle M Baumann, Trevor J Beardsley, Magdalena A Taracila, Susan D Rudin, Kristine M Hujer and 8 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of medicinal chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
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  4. Article
  5. β-Lactamase diversity inAntimicrobial agents and chemotherapy · 2025
    Article
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 3 institutions in 2 countries.

Rachel A PowersDepartment of Chemistry, Grand Valley State University, Allendale, Michigan 49401, United States.ORCID 0000-0002-9968-8284
Cynthia M JuneDepartment of Chemistry, Grand Valley State University, Allendale, Michigan 49401, United States.ORCID 0000-0003-3327-4238
Micah C FernandoDepartment of Chemistry, Grand Valley State University, Allendale, Michigan 49401, United States.ORCID 0000-0001-9779-0667
Erin R FishDepartment of Chemistry, Grand Valley State University, Allendale, Michigan 49401, United States.
Olivia L MaurerDepartment of Chemistry, Grand Valley State University, Allendale, Michigan 49401, United States.
Rachelle M BaumannDepartment of Chemistry, Grand Valley State University, Allendale, Michigan 49401, United States.
Trevor J BeardsleyDepartment of Chemistry, Grand Valley State University, Allendale, Michigan 49401, United States.
Magdalena A TaracilaDepartment of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, United States.
Susan D RudinDepartment of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, United States.
Kristine M HujerDepartment of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, United States.
Andrea M HujerDepartment of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, United States.
Nicolò SantiDepartment of Life Sciences, University of Modena and Reggio Emilia, via Campi 103, Modena 41125, Italy.ORCID 0000-0001-6361-5457
Valentina VillamilDepartment of Life Sciences, University of Modena and Reggio Emilia, via Campi 103, Modena 41125, Italy.
Maria Luisa IntrovigneDepartment of Life Sciences, University of Modena and Reggio Emilia, via Campi 103, Modena 41125, Italy.
Fabio PratiDepartment of Life Sciences, University of Modena and Reggio Emilia, via Campi 103, Modena 41125, Italy.ORCID 0000-0002-0650-9540
Emilia CaselliDepartment of Life Sciences, University of Modena and Reggio Emilia, via Campi 103, Modena 41125, Italy.ORCID 0000-0002-7248-9453
Robert A BonomoDepartment of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, United States.ORCID 0000-0002-3299-894X
Bradley J WallarDepartment of Chemistry, Grand Valley State University, Allendale, Michigan 49401, United States.ORCID 0000-0002-1466-4794
Grand Valley State University · USLouis Stokes Cleveland VA Medical Center · USUniversity of Modena and Reggio Emilia · IT

Funding

Understanding B-Lactam Resistance in Acinetobacter baumanniiR01AI072219 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI ROBERT A. BONOMO, Philip N. Rather · 2007 to 2026
$6.6M
NIAID NIH HHS R01 AI072219
6 · The paper itself

Abstract

Class C

Indexed as

Acinetobacter baumanniiCephalosporinaseAnti-Bacterial Agentsbeta-LactamasesBoronic AcidsCephalosporinsMicrobial Sensitivity TestsAnti-Bacterial Agentsbeta-LactamasesBoronic AcidsCephalosporinaseCephalosporins

Identifiers

PMID37358467
PMCPMC10350917
OpenAlexW4382011063

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.