Evidence map›Paper›PMID 37358415›Full record

ArticleMicrobiology spectrum2023

Molecular Characterization and Sterol Profiles Identify Nonsynonymous Mutations in

Mohammad Asadzadeh, Wadha Alfouzan, Josie E Parker, Jacques F Meis, Steven L Kelly, Leena Joseph, Suhail Ahmad

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Micafungin exposure drives multidrug resistance inbioRxiv : the preprint server for biology · 2026
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  4. Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2026
    Article
  5. Osh2 mediatesAntimicrobial agents and chemotherapy · 2025
    Article
  6. Article
  7. The multidrug-resistantCurrent research in microbial sciences · 2025
    Review
  8. Genetic microevolution of clinicalEmerging microbes & infections · 2024
    Article
  9. Article
  10. Article
  11. Spectrum and management of rareTherapeutic advances in infectious disease
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 4 countries.

Mohammad AsadzadehDepartment of Microbiology, Faculty of Medicine, Kuwait University, Safat, Kuwait.
Wadha AlfouzanDepartment of Microbiology, Faculty of Medicine, Kuwait University, Safat, Kuwait.
Josie E ParkerMolecular Biosciences Division, School of Biosciences, Cardiff University, Cardiff, United Kingdom.
Jacques F MeisDepartment of Medical Microbiology and Infectious Diseases, Canisius-Wilhelmina Hospital, Nijmegen, the Netherlands.ORCID 0000-0003-3253-6080
Steven L KellyInstitute of Life Science, Faculty of Health, Medicine and Life Sciences, Swansea University, Swansea, Wales, United Kingdom.
Leena JosephDepartment of Microbiology, Faculty of Medicine, Kuwait University, Safat, Kuwait.
Suhail AhmadDepartment of Microbiology, Faculty of Medicine, Kuwait University, Safat, Kuwait.ORCID 0000-0003-3492-4781
Kuwait University · KWCardiff University · GBRadboud University Nijmegen · NLSwansea University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The molecular basis of reduced susceptibility to amphotericin B (rs-AMB) among any yeasts is poorly defined. Genetic alterations in genes involved in ergosterol biosynthesis and total cell sterols were investigated among clinical Candida kefyr isolates. C. kefyr isolates (

Indexed as

Amphotericin BAntifungal AgentsErgosterolHumansKluyveromycesMutationSterolsAmphotericin BAntifungal AgentsErgosterolSterolsamphotericin BCandida kefyrERG2nonsynonymous mutationsreduced susceptibility

Identifiers

PMID37358415
PMCPMC10434000
OpenAlexW4382010542

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.