Evidence map›Paper›PMID 37358297›Full record

ArticlemSphere2023

Redefining pleiotropic drug resistance in a pathogenic yeast: Pdr1 functions as a sensor of cellular stresses in

Andrew N Gale, Matthew W Pavesic, Timothy J Nickels, Zhuwei Xu, Brendan P Cormack, Kyle W Cunningham

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 22 citations in OpenAlex.

  1. Facile generation ofMicrobiology spectrum · 2026
    Article
  2. Article
  3. The azole-resistance phenotype of aMicrobiology spectrum · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Frontiers in microbiology · 2026
    Article
  8. Tn-seq screens inmSphere · 2025
    Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. mSphere · 2024
    Article
  16. Microbe Profile:Microbiology (Reading, England) · 2024
    Review
  17. Similarities and distinctions in the activation of thebioRxiv : the preprint server for biology · 2024
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Andrew N GaleDepartment of Biology, Johns Hopkins University , Baltimore, Maryland, USA.
Matthew W PavesicDepartment of Biology, Johns Hopkins University , Baltimore, Maryland, USA.
Timothy J NickelsDepartment of Biology, Johns Hopkins University , Baltimore, Maryland, USA.
Zhuwei XuDepartment of Molecular Biology and Genetics, Johns Hopkins University School of Medicine , Baltimore, Maryland, USA.
Brendan P CormackDepartment of Molecular Biology and Genetics, Johns Hopkins University School of Medicine , Baltimore, Maryland, USA.
Kyle W CunninghamDepartment of Biology, Johns Hopkins University , Baltimore, Maryland, USA.ORCID 0000-0001-6877-6321
Johns Hopkins University · US

Funding

CELLULAR AND MOLECULAR BIOLOGYT32GM007231 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI VAN DOREN, MARK B · 1985 to 2020
$18.4M
AIDS Opportunistic Infectious: Virulence of C. glabrataR01AI046223 · NIAID · JOHNS HOPKINS UNIVERSITY · PI CORMACK, BRENDAN · 1999 to 2014
$4.9M
Mechanisms Promoting Cellular Tolerance to FungistatsR01AI153414 · NIAID · JOHNS HOPKINS UNIVERSITY · PI CUNNINGHAM, KYLE W · 2020 to 2023
$1.6M
NIAID NIH HHS R01 AI046223NIAID NIH HHS R01 AI153414NIGMS NIH HHS T32 GM007231
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antifungal AgentsFluconazoleFungal ProteinsTranscription FactorsCandida glabrataCycloheximideDrug Resistance, FungalHumansXenobioticsAntifungal AgentsCycloheximideFluconazoleFungal ProteinsPdr1 protein, Candida glabrataTranscription FactorsXenobioticsantifungal resistancedrug interactionsmechanisms of resistance

Identifiers

PMID37358297
PMCPMC10449514
OpenAlexW4382010633

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.