Evidence map›Paper›PMID 37358226›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2023

Two-Year Outcomes of Treatment-Experienced Adults After Programmatic Transitioning to Dolutegravir: Longitudinal Data From the VICONEL Human Immunodeficiency Virus Cohort in Lesotho.

Nadine Tschumi, Malebanye Lerotholi, Lipontso Motaboli, Moliehi Mokete, Niklaus D Labhardt, Jennifer A Brown

Abstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Viral Suppression, Viral Failure, and Safety Outcomes in Children and Adolescents With HIV on Dolutegravir in Europe and Thailand.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Virologic Failure and Drug Resistance After Programmatic Switching to Dolutegravir-based First-line Antiretroviral Therapy in Malawi and Zambia.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025
    Observational
  12. Article
  13. Review
  14. Emergence of Acquired Dolutegravir Resistance in Treatment-experienced People With HIV in Lesotho.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
    Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nadine TschumiDivision of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.ORCID 0000-0002-7303-9542
Malebanye LerotholiDivision of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.ORCID 0000-0003-2101-6143
Lipontso MotaboliSolidarMed, Partnerships for Health, Maseru, Lesotho.
Moliehi MoketeSolidarMed, Partnerships for Health, Maseru, Lesotho.
Niklaus D LabhardtDivision of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.ORCID 0000-0003-3599-1791
Jennifer A BrownDivision of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.ORCID 0000-0003-1874-6153

Funding

Swiss National Science Foundation PCEFP3_181355
6 · The paper itself

Abstract

In the Viral Load Cohort North-East Lesotho (VICONEL) human immunodeficiency virus cohort, 14 242 adults had transitioned from efavirenz- or nevirapine-based antiretroviral therapy (ART) to dolutegravir-based ART by October 2021. Rates of viral suppression to <50 copies/mL were 84.8%, 93.9%, and 95.4% before, 12 months after, and 24 months after transition, respectively. Sex, age, pretransition viral load, and treatment backbone correlated with 24-month viremia.

Indexed as

Anti-HIV AgentsHIV InfectionsAdultDolutegravirHeterocyclic Compounds, 3-RingHIVHumansLesothoTreatment OutcomeViral LoadAnti-HIV AgentsDolutegravirHeterocyclic Compounds, 3-RingAfricaintegrase inhibitorsobservational studytreatment failuretreatment outcome

Identifiers

PMID37358226
PMCPMC10640687

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.