Evidence map›Paper›PMID 37358144›Full record

ArticleGut microbes

Dietary sugars silence the master regulator of carbohydrate utilization in human gut Bacteroides species.

Victoria H Pearce, Eduardo A Groisman, Guy E Townsend

Open access · goldAbstract read
In one paragraph

Article in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. A conserved peptidase governs glucose homeostasis inbioRxiv : the preprint server for biology · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Determinants of raffinose family oligosaccharide use inbioRxiv : the preprint server for biology · 2024
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Victoria H PearceBiochemistry & Molecular Biology, Penn State College of Medicine, Hershey, PA, USA.ORCID 0000-0002-7599-4076
Eduardo A GroismanMicrobial Pathogenesis, Yale University School of Medicine, New Haven, CT, USA.ORCID 0000-0001-6860-7691
Guy E TownsendBiochemistry & Molecular Biology, Penn State College of Medicine, Hershey, PA, USA.ORCID 0000-0002-8231-3769
Pennsylvania State University · USYale University · US

Funding

Control of gut colonization by the prominent gut bacterium Bacteroides thetaiotaomicronR01GM123798 · NIGMS · YALE UNIVERSITY · PI GROISMAN, EDUARDO · 2018 to 2025
$2.7M
Harnessing the gut microbiome to detect and quantify glycansR01GM147178 · NIGMS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI TOWNSEND, GUY EDMUND · 2022 to 2025
$1.8M
NIGMS NIH HHS R01 GM123798NIGMS NIH HHS R01 GM147178
6 · The paper itself

Abstract

The mammalian gut microbiota is a critical human health determinant with therapeutic potential for remediation of many diseases. The host diet is a key factor governing the gut microbiota composition by altering nutrient availability and supporting the expansion of distinct microbial populations. Diets rich in simple sugars modify the abundance of microbial subsets, enriching for microbiotas that elicit pathogenic outcomes. We previously demonstrated that diets rich in fructose and glucose can reduce the fitness and abundance of a human gut symbiont,

Indexed as

BacteroidesGastrointestinal MicrobiomeAnimalsDietary SugarsFructoseGlucoseHumansMammalsDietary SugarsFructoseGlucoseBacteroidescarbohydrate utilizationdietary sugarfructoseglucosegut microbiometranscription regulation

Identifiers

PMID37358144
PMCPMC10294740
OpenAlexW4382010852

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.