Evidence map›Paper›PMID 37358000›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2023

Phage-Inducible Chromosomal Islands as a Diagnostic Platform to Capture and Detect Bacterial Pathogens.

Rodrigo Ibarra-Chávez, Julien Reboud, José R Penadés, Jonathan M Cooper

Open access · goldAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 4 countries.

Rodrigo Ibarra-ChávezDepartment of Biology, Section of Microbiology, University of Copenhagen, Universitetsparken 15, bldg. 1, Copenhagen, DK2100, Denmark.ORCID 0000-0002-9056-3055
Julien ReboudDivision of Biomedical Engineering, James Watt School of Engineering, University of Glasgow, Glasgow, G12 8QQ, UK.ORCID 0000-0002-6879-8405
José R PenadésInstitute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, G12 8TA, UK.ORCID 0000-0002-6439-5262
Jonathan M CooperDivision of Biomedical Engineering, James Watt School of Engineering, University of Glasgow, Glasgow, G12 8QQ, UK.ORCID 0000-0002-2358-1050
University of Glasgow · GBUniversidad Cardenal Herrera CEU · ESUniversity of Copenhagen · DK

Funding

Medical Research Council MC_PC_17160Medical Research Council MR/M003876/1Medical Research Council MR/S00940X/1
6 · The paper itself

Abstract

Phage-inducible chromosomal islands (PICIs) are a family of phage satellites that hijack phage components to facilitate their mobility and spread. Recently, these genetic constructs are repurposed as antibacterial drones, enabling a new toolbox for unorthodox applications in biotechnology. To illustrate a new suite of functions, the authors have developed a user-friendly diagnostic system, based upon PICI transduction to selectively enrich bacteria, allowing the detection and sequential recovery of Escherichia coli and Staphylococcus aureus. The system enables high transfer rates and sensitivities in comparison with phages, with detection down to ≈50 CFU mL

Indexed as

BacteriophagesBacteriaEscherichia coliGenomic IslandsIslandsbacterial detectiondiagnosticsmobile genetic elementspaper microfluidicsphage satellitesPICIs

Identifiers

PMID37358000
PMCPMC10460865
OpenAlexW4382011093

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.