Evidence map›Paper›PMID 37357749›Full record

ArticleJournal of the American Chemical Society2023

RNA-Polymer Hybrids via Direct and Site-Selective Acylation with the ATRP Initiator and Photoinduced Polymerization.

Jaepil Jeong, Xiaolei Hu, Hironobu Murata, Grzegorz Szczepaniak, Marta Rachwalak, Anna Kietrys, Subha R Das, Krzysztof Matyjaszewski

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Robust Miniemulsion PhotoATRP Driven by Red and Near-Infrared Light.Journal of the American Chemical Society · 2024
    Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jaepil JeongDepartment of Chemistry, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, United States.
Xiaolei HuDepartment of Chemistry, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, United States.
Hironobu MurataDepartment of Chemistry, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, United States.
Grzegorz SzczepaniakDepartment of Chemistry, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, United States.
Marta RachwalakDepartment of Chemistry, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, United States.
Anna KietrysDepartment of Chemistry, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, United States.
Subha R DasDepartment of Chemistry, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, United States.ORCID 0000-0002-5353-0422
Krzysztof MatyjaszewskiDepartment of Chemistry, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, United States.ORCID 0000-0003-1960-3402

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Combining synthetic polymers with RNA paves the way for creating RNA-based materials with non-canonical functions. We have developed an acylation reagent that allows for direct incorporation of the atom transfer radical polymerization (ATRP) initiator into both short synthetic oligoribonucleotides and natural biomass RNA extracted from torula yeast. The acylation was performed in a quantitative yield. The resulting initiator-functionalized RNAs were used for grafting polymer chains from the RNA by photoinduced ATRP, resulting in RNA-polymer hybrids with narrow molecular weight distributions. The RNA initiator was used for the polymerization of oligo(ethylene oxide) methyl ether methacrylate, poly(ethylene glycol) dimethacrylate, and

Indexed as

Polyethylene GlycolsPolymersMethacrylatesPolymerizationMethacrylatespoly(ethylene glycol)-dimethacrylatePolyethylene GlycolsPolymers

Identifiers

PMID37357749
PMCPMC10326879

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.