Evidence map›Paper›PMID 37357513›Full record

ArticleEndocrine, metabolic & immune disorders drug targets2023

Doege-Potter Syndrome; A Case of Solitary Fibrous Pleura Tumor Associated with Severe Hypoglycemia: A Case Report in Internal Medicine.

Viviana Castaldo, Daniela Domenici, Mauro Valentino Biscosi, Paolo Ubiali, Cesare Miranda, Giorgio Zanette, Cinzia Mazzon, Maurizio Tonizzo

Open access · greenAbstract readCase Reports
In one paragraph

Article in Endocrine, metabolic & immune disorders drug targets, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Viviana CastaldoDepartment of Internal Medicine, Hospital Santa Maria degli Angeli, Pordenone, Italy.
Daniela DomeniciDepartment of Endocrinology and Metabolic Diseases, Hospital Santa Maria degli Angeli, Pordenone, Italy.
Mauro Valentino BiscosiDepartment of Radiology, Hospital Santa Maria degli Angeli, Pordenone, Italy.
Paolo UbialiDepartment of General Surgery, Hospital Santa Maria degli Angeli, Pordenone, Italy.
Cesare MirandaDepartment of Endocrinology and Metabolic Diseases, Hospital Santa Maria degli Angeli, Pordenone, Italy.
Giorgio ZanetteDepartment of Endocrinology and Metabolic Diseases, Hospital Santa Maria degli Angeli, Pordenone, Italy.
Cinzia MazzonDepartment of Endocrinology and Metabolic Diseases, Hospital Santa Maria degli Angeli, Pordenone, Italy.
Maurizio TonizzoDepartment of Internal Medicine, Hospital Santa Maria degli Angeli, Pordenone, Italy.
Azienda Ospedaliera Santa Maria Degli Angeli · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDoege-Potter syndrome is a rare paraneoplastic entity that is often diagnosed incidentally during the work-up of hypoglycemia of unclear etiology. It is characterized by a non-islet cell tumor hypoglycemia mostly associated with solitary fibrous tumors. These uncommon tumors have been reported in <5% of solitary fibrous tumors. Although not unique in its kind, this case is extremely important as this syndrome often conceals unrecognized tumors that can be surgically resolved. CASE PRESENTATION: We present the case of a 59-year-old non-diabetic man with a 2-month history of severe and recurrent fasting hypoglycaemia presenting with severe dyspnea and sweating. Further workup revealed low insulin, C-peptide, and IGF-1 levels and a large right in-trathoracic solitary fibrous tumor. Unfortunately, bioassays for IGF-2 were unavailable at our hos-pital. Nevertheless, as hypoglycemia completely resolved after resection of the mass, Doege-Potter syndrome was highly suspected.

conclusionDoege-Potter syndrome is a complication of rare tumors. If hy-poglycemia is unexplained, this syndrome should always be suspected, and the presence of un-known masses should be investigated.

Indexed as

HypoglycemiaSolitary Fibrous Tumor, PleuralCongenital AbnormalitiesHumansKidneyKidney DiseasesMaleMiddle AgedPleuraSyndromeUrogenital Abnormalitiesdoege-potter syndromeHypoglycemiaIGF-2non-islet cell tumor hypoglycemiasolitary fibrous tumorSTAT6

Identifiers

PMID37357513
PMCPMC10548549
OpenAlexW4382011814

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.