Trial reportThe journal of nutrition, health & aging2023
The Effectiveness of Frailty Intervention for Older Patients with Frailty during Hospitalization.
Trial report in The journal of nutrition, health & aging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07027241 (Multicomponent Exercise and Nutrition Based Frailty Intervention in Postoperative Hip Fracture Inpatients), which is not on this map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Multicomponent Exercise and Nutrition Based Frailty Intervention in Postoperative Hip Fracture Inpatients
Who cites it
14 citing papers in PubMed, 16 citations in OpenAlex.
- Frailty and outcomes in older adults hospitalized for epilepsy: a nationwide inpatient sample study.BMC geriatrics · 2026Article
- The Trajectory of Activities of Daily Living and Its Influencing Factors in Older Adults: A Longitudinal Study.Nursing open · 2026Article
- Implementation of a best practice advisory alert for inpatient frailty screening and intervention: A pilot quality improvement program.The Journal of frailty & aging · 2026Article
- Frailty Alerts Reduce Waiting Time and Length of Stay in the Emergency Department.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2026Observational
- Development and validation of a Chinese version of the frailty risk perception questionnaire for older adults with colorectal cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Effects of multimodal nursing intervention with health education on recovery, pain, and psychological outcomes after laparoscopic cholecystectomy: a retrospective cohort study.Frontiers in surgery · 2025Article
- Prevalence of physical frailty and its associated factors among elderly patients undergoing hepatobiliary pancreatic surgery in China.Global health & medicine · 2024Article
- The application of machine learning for identifying frailty in older patients during hospital admission.BMC medical informatics and decision making · 2024Article
- Effect of leisure activity on frailty trajectories among Chinese older adults: a 16-year longitudinal study.BMC geriatrics · 2024Article
- Article
- Construction of frailty and risk prediction models in maintenance hemodialysis patients: a cross-sectional study.Frontiers in medicine · 2024Article
- Editorial: Towards a Real Personalized Geriatric Medicine: The Example of the Prevention of Hospital-Acquired Disability.The journal of nutrition, health & aging · 2023Article
- Development and Validation of a Risk Prediction Model for Frailty in Patients with Chronic Diseases.Gerontology & geriatric medicineArticle
- Article
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThis study aims to assess the effectiveness of a multidomain intervention program on the change in functional status of hospitalized older adults.
designThis single-arm, prospective, non-randomized interventional study investigates the efficacy of a multidomain interventional program including cognitive stimulation activity, simple exercises, frailty education, and nutrition counseling. SETTING AND
participantsAt a tertiary hospital in southern Taiwan, 352 eligible patients were sequentially enrolled. Included patients were aged ≥65 years (mean age, 79.6 ± 9.0 years; 62% male), scored 3-7 on the Clinical Frailty Scale (CFS), and were hospitalized in the geriatric acute ward.
interventionThose receiving standard care (physical rehabilitation and nutrition counseling) during January-July 2019 composed the historical control group. Those receiving the multidomain intervention during August-December 2019 composed the intervention group. MEASUREMENTS: The primary outcome was the change in activities of daily life (ADL) and frailty status, as assessed by Katz Index and Clinical Frailty Scale, with using the generalized estimating equation model. The length of hospital stay, medical costs, and re-admission rates were secondary outcomes.
resultsParticipants undergoing intervention (n = 101; 27.9%) showed greater improvements in the ADL and CFS during hospitalization (ADL adjusted estimate, 0.61; 95% CI, 0.11-1.11; p = 0.02; CFS adjusted estimate, -1.11; 95% CI, -1.42- -0.80; p < 0.01), shorter length of hospital stay (adjusted estimate, -5.00; 95% CI, -7.99- -2.47; p < 0.01), lower medical costs (adjusted estimate, 0.58; 95% CI, 0.49-0.69; p < 0.01), and lower 30- and 90-day readmission rates (30-day adjusted OR [aOR], 0.12; 95% CI, 0.27-0.50; p < 0.01; 60-day aOR, 0.04; 95% CI, 0.01-0.33; p < 0.01) than did controls.
conclusionsParticipation in the multidomain intervention program during hospitalization improved the functional status and decreased the hospital stay length, medical costs, and readmission rates of frail older people.
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