Evidence map›Paper›PMID 37356412›Full record

ArticleClinics (Sao Paulo, Brazil)2023

A longitudinal study of the peripheral and central auditory pathways in individuals with acute lymphoid leukemia.

Jéssica Sales Vosgrau, Liliane Aparecida Fagundes Silva, Vicente Odone Filho, Carla Gentile Matas

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinics (Sao Paulo, Brazil), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jéssica Sales VosgrauDepartment of Physical Therapy, Speech-language Pathology and Audiology, and Occupational Therapy, Faculdade de Medicina (FMUSP), Universidade de São Paulo, São Paulo, SP, Brazil. Electronic address: jevosgrau@gmail.com.
Liliane Aparecida Fagundes SilvaDepartment of Physical Therapy, Speech-language Pathology and Audiology, and Occupational Therapy, Faculdade de Medicina (FMUSP), Universidade de São Paulo, São Paulo, SP, Brazil.
Vicente Odone FilhoDepartment of Pediatrics, Faculdade de Medicina (FMUSP), Universidade de São Paulo, São Paulo, SP, Brazil.
Carla Gentile MatasDepartment of Physical Therapy, Speech-language Pathology and Audiology, and Occupational Therapy, Faculdade de Medicina (FMUSP), Universidade de São Paulo, São Paulo, SP, Brazil.
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BRUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo characterize the peripheral and central auditory pathways in individuals with Acute Lymphoid Leukemia (ALL) and compare assessment results before and during chemotherapy.

methodThe study included 17 subjects with ALL, divided into two age groups: 3 to 6 (11 individuals) and 7 to 16 years old (6 individuals). Each subject was evaluated twice (before and 3 to 6 months after chemotherapy treatment) with the following procedures: medical history survey, otoscopy, Pure-Tone Threshold (PTA) and speech audiometry, acoustic immittance measures, Brainstem Auditory Evoked Potentials (BAEP) and Long-Latency Auditory Evoked Potentials (LLAEP).

resultsPTA was normal. Tympanometry was abnormal in the second assessment in 2 individuals aged 3 to 6 years. One subject in each age group had absent ipsilateral acoustic reflexes. In high-frequency audiometry, 1 individual had abnormal results. BAEP was abnormal in 5 (first assessment) and 7 individuals (second assessment) aged 3 to 6 years and 2 (first assessment) and 1 individual (second assessment) aged 7 to 16 years. As for LLAEP, P1 latency was increased in 5 (first assessment) and 7 individuals (second assessment) aged 3 to 6 years.

conclusionNo hearing loss was identified in the behavioral audiological assessment. BAEP was more affected in the 3-to-6-year-old group, with greater impairment in the lower brainstem in the first and second assessments. In LLAEP, P1 was the most impaired component in children aged 3 to 6 years, and P2 and N2 were so for those 7 to 16 years old, especially in the second assessment.

Indexed as

Auditory PathwaysPrecursor Cell Lymphoblastic Leukemia-LymphomaAdolescentAudiometry, Pure-ToneChildChild, PreschoolEvoked Potentials, AuditoryEvoked Potentials, Auditory, Brain StemHumansInfantLongitudinal StudiesAuditory evoked potentialsAuditory perceptionHearingLeukemia-lymphoblastic precursor cell lymphomaPharmacological treatment

Identifiers

PMID37356412
PMCPMC10310478
OpenAlexW4381848703

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.