ArticleOphthalmology and therapy2023
Qualitative Exploration of the Visual Function Impairments and Health-Related Quality of Life Impacts of Amblyopia in Adult and Pediatric Populations.
Article in Ophthalmology and therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 14 citations in OpenAlex.
- Equivalent effectiveness of a prescription binocular treatment for amblyopia in real-world practice.Journal of managed care & specialty pharmacy · 2026Article
- Psychometric Performance of Children With Amblyopia During a Tablet-Based Adaptive Visual Acuity Assessment.Investigative ophthalmology & visual science · 2026Article
- Real world gains stable in children with amblyopia following digital dichoptic treatment: PUPiL registry results.BMC ophthalmology · 2026Article
- Refractive Error Patterns and the Impact of Cycloplegia in Ametropic Children and Adolescents in Al-Baha, Saudi Arabia.Clinical optometry · 2026Article
- Visuo-Cognitive Executive Functions in Amblyopia and Strabismus: Associations With Function and Quality of Life.Investigative ophthalmology & visual science · 2025Article
- Health-related quality of life and its associated factors among high school students with myopia in China.BMC public health · 2025Article
- Recommendations for use and coverage of digital, binocular treatments for amblyopia.Journal of managed care & specialty pharmacy · 2025Article
- Psychometric validation of the SNAP-IV rating scale in amblyopic children at high AD/HD risk: structural validity and measurement invariance.Frontiers in psychiatry · 2025Article
- Decreased scene-selective activity within the posterior intraparietal cortex in amblyopic adults.Frontiers in neuroscience · 2025Article
- Fine Motor Skills, Reading Speed, and Self-Reported Quality of Life in Adults With Amblyopia and/or Strabismus.Investigative ophthalmology & visual science · 2024Article
- Decreased scene-selective activity within the posterior intraparietal cortex in amblyopic adults.bioRxiv : the preprint server for biology · 2024Article
- The Amblyopia Quality of Life (AmbQoL): Development and Content Validation of a Novel Health-Related Quality of Life Instrument for Use in Adult and Pediatric Amblyopia Populations.Ophthalmology and therapy · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 5 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAmblyopia is a reduction in vision in one or both eyes due to impaired development of the visual pathway. This study explored the experience of amblyopia and treatment from the patient, caregiver, and clinician perspectives.
methodsA targeted literature review, including a review of social media listening (SML) studies, was conducted. Next, qualitative interviews were conducted with amblyopia patients, caregivers of children with amblyopia, and ophthalmologists with experience treating patients with amblyopia. The findings informed the development of a disease model. Amblyopia clinical experts provided input at key stages.
resultsTwelve data sources were reviewed, including qualitative studies in the literature and SML studies. Overall, 133 patients/caregivers were interviewed (23 adults, 16 adolescents, 47 child-caregiver dyads), plus 10 ophthalmologists from the United States, France, and Germany. Reduced visual acuity, impaired depth perception, impaired peripheral vision, and double vision were the most frequently reported symptoms. Amblyopia impacted daily activities (reading, using digital devices), the ability to move around, school/work (productivity, seeing the board in class), emotional well-being (frustration, sadness), and social functioning (difficulty socializing). Treatments, including patching and corrective lens, also impacted daily activities (using digital devices, sports/leisure), mobility (bumping into things), and work/school (tasks taking longer) as well as emotional well-being (embarrassment), and social functioning (bullying/stigma).
conclusionThe findings contribute valuable insights into the adult and pediatric experience of amblyopia from a multi-stakeholder perspective. The findings were used to critically assess existing clinical outcome assessments and supported the development of patient- and observer-reported outcome measures for use in amblyopia clinical trials.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.