ArticleAlzheimer's research & therapy2023
Association study between drug prescriptions and Alzheimer's disease claims in a commercial insurance database.
Article in Alzheimer's research & therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- Agglomerative clustering-based drugs graded for the risk signals of drug-induced cognitive disorder: a study on the FAERS database.Therapeutic advances in drug safety · 2026Article
- Estimating the burden of dementia and parkinsonism through a novel identification algorithm based on healthcare administrative data.Frontiers in public health · 2025Article
- Prescription medication use in the 10 years prior to diagnosis of young onset Alzheimer's disease: a nationwide nested case-control study.Alzheimer's research & therapy · 2024Article
- A study protocol for identifying aging trajectories toward chronic neurodegenerative diseases by means of Marche regional administrative databases - TREND project.Frontiers in public health · 2024Article
- Data-driven discovery of associations between prescribed drugs and dementia risk: A systematic review.Alzheimer's & dementia (New York, N. Y.)Review
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Authors and funding
4 authors.
Funding
Abstract
In the ongoing effort to discover treatments for Alzheimer's disease (AD), there has been considerable focus on investigating the use of repurposed drug candidates. Mining of electronic health record data has the potential to identify novel correlated effects between commonly used drugs and AD. In this study, claims from members with commercial health insurance coverage were analyzed to determine the correlation between the use of various drugs on AD incidence and claim frequency. We found that, within the insured population, several medications for psychotic and mental illnesses were associated with higher disease incidence and frequency, while, to a lesser extent, antibiotics and anti-inflammatory drugs were associated with lower AD incidence rates. The observations thus provide a general overview of the prescription and claim relationships between various drug types and Alzheimer's disease, with insights into which drugs have possible implications on resulting AD diagnosis.
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Registered trials
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