Evidence map›Paper›PMID 37355542›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2023

Tracking Cardiovascular Comorbidity in Models of Chronic Inflammatory Disease.

Aisling S Morrin, Simon Eastham, Anwen S Williams, Gareth W Jones

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 76% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Aisling S MorrinDivision of Infection and Immunity, and Systems Immunity University Research Institute, School of Medicine, Cardiff University, Cardiff, Wales, UK.
Simon EasthamSchool of Cellular and Molecular Medicine, Biomedical Sciences Building, University of Bristol, Bristol, UK.
Anwen S WilliamsDivision of Infection and Immunity, and Systems Immunity University Research Institute, School of Medicine, Cardiff University, Cardiff, Wales, UK.
Gareth W JonesSchool of Cellular and Molecular Medicine, Biomedical Sciences Building, University of Bristol, Bristol, UK. g.jones@bristol.ac.uk.
Cardiff University · GBUniversity of Bristol · GB

Funding

Versus Arthritis 20305Versus Arthritis 22706Versus Arthritis 5149 / 5150
6 · The paper itself

Abstract

Immune-mediated inflammatory diseases (IMIDs) are commonly associated with complex coexisting conditions, and cardiovascular comorbidities are a common cause of mortality in systemic inflammation. Experimental models of disease provide an opportunity to dissect inflammatory mechanisms that promote damage to vascular tissues affected by comorbidity. Here, we describe methods to recover the thoracic aorta from mice during experimental inflammatory arthritis and assess vascular constriction responses by isometric tension myography. To complement the assessment of functional changes in the vasculature during inflammatory arthritis, we also outline a method to characterize vascular inflammation by immunohistochemistry.

Indexed as

Arthritis, ExperimentalCardiovascular DiseasesAnimalsAorta, ThoracicComorbidityInflammationMiceCardiovascular comorbidityHistopathologyInflammatory arthritisIsometric tension myographyRheumatoid arthritisVascular contractile dysfunction

Identifiers

PMID37355542
OpenAlexW4381888286

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.