Evidence map›Paper›PMID 37355490›Full record

ArticleSpine deformity2023

Radiographic and perioperative outcomes following anterior thoracic vertebral body tethering and posterior lumbar spine tethering: a pilot series.

Jeremy W Siu, Hao-Hua Wu, Satvir Saggi, Sachin Allahabadi, Toshali Katyal, Mohammad Diab

Open access · hybridAbstract read
In one paragraph

Article in Spine deformity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. The Effects of Vertebral Body Tethering on the Intervertebral Discs and Facet Joints: A Numerical Analysis.International journal for numerical methods in biomedical engineering · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. What's new in the pediatric spine?Journal of children's orthopaedics · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jeremy W SiuSan Francisco School of Medicine, University of California, San Francisco, CA, USA. Jeremy.siu@ucsf.edu.ORCID http://orcid.org/0000-0001-8474-862X
Hao-Hua WuDepartment of Orthopaedic Surgery, University of California, San Francisco, CA, USA.
Satvir SaggiSan Francisco School of Medicine, University of California, San Francisco, CA, USA.ORCID http://orcid.org/0000-0002-4511-367X
Sachin AllahabadiDepartment of Orthopaedic Surgery, University of California, San Francisco, CA, USA.ORCID http://orcid.org/0000-0002-1185-3039
Toshali KatyalDepartment of Orthopaedic Surgery, University of California, San Francisco, CA, USA.ORCID http://orcid.org/0000-0003-2200-681X
Mohammad DiabDepartment of Orthopaedic Surgery, University of California, San Francisco, CA, USA.
University of California, San Francisco · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and contextIn patients with adolescent idiopathic scoliosis (AIS) of main thoracic and lumbar spine regions, combined anterior thoracic vertebral body tethering and posterior lumbar spine tethering (ATVBT/PLST) is a novel non-fusion treatment option for growth modulation and conservation of motion.

methodsFourteen patients with AIS who underwent ATVBT/PLST with at least 2-year follow-up were included. Primary outcomes included quality of life as assessed by SRS-22 instruments, radiographic analysis, and revision operations. We secondarily reported perioperative metrics and post-operative opiate morphine equivalents (OME). Clinical success was defined as patients who achieved skeletal maturity with ≤ 30° curve magnitude of both their main thoracic and thoracolumbar/lumbar curves and who did not undergo posterior spine instrumentation and fusion (PSIF).

resultsPatients had a mean age of 11.6 years (range 10-14 years), majority were girls (92%), and mean follow-up was 3.0 years (range 2-4.8 years). All patients were skeletally immature with a Risser ≤ 2. Included curves were Lenke 1C, 3C, or 6C. Mean preoperative curve magnitudes were 53° ± 8° (range 45°-65°) main thoracic and 49° ± 9° (range 40°-62°) thoracolumbar/lumbar curves. At most recent follow-up, patients had a mean main thoracic curve of 29° ± 8° (range 15°-40°) and a mean thoracolumbar/lumbar curve of 20° ± 15° (range 4°-35°). 50% required a revision operation. Cable breakage occurred in 43%, which did not always require revision. One patient progressed to thoracic fusion, but no patient underwent lumbar fusion. Patients had a mean SRS-22 outcome score of 4.2 ± 0.4.

conclusionsATVBT/PLST is a potential alternative to spine fusion for select immature patients with AIS at a minimum 2-year follow-up. ATVBT/PLST potentially offers motion conservation at the cost of a higher revision rate. Further study and reporting of results are necessary to refine indications and techniques, which in turn will improve outcomes of this procedure. LEVEL OF EVIDENCE: Level IV-Case series without comparative group.

Indexed as

Lumbar VertebraeScoliosisThoracic VertebraeVertebral BodyAdolescentChildFemaleFollow-Up StudiesHumansMalePilot ProjectsQuality of LifeRadiographyReoperationSpinal FusionTreatment OutcomeAdolescent idiopathic scoliosisCable breakagePosterior lumbar spine tetheringRevision operationVertebral body tethering

Identifiers

PMID37355490
PMCPMC10587020
OpenAlexW4381943684

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.