ArticleBMJ open2023
Association between Triglyceride-Glucose Index and carotid plaque in Japanese population: a cross-sectional study.
Article in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 12 citations in OpenAlex.
- Association of triglyceride-glucose index with carotid atherosclerosis in the general population: a case-control study of 14,535 participants.BMC cardiovascular disorders · 2026Article
- Association between systemic inflammation indices and carotid plaques in acute coronary syndrome.Frontiers in cardiovascular medicine · 2026Article
- Association between the triglyceride-glucose index and subclinical atherosclerosis in asymptomatic adults: a large cross-sectional study of a health check-up population.Frontiers in cardiovascular medicine · 2026Article
- Non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio is associated with cardiovascular outcomes after percutaneous coronary intervention in patients with type 2 diabetes.Frontiers in endocrinology · 2026Article
- Triglyceride-glucose index as a biomarker to differentiate stroke etiologic subtypes: a hospital-based cross-sectional study.Biomarkers in medicine · 2025Article
- The Impact of Triglyceride-Glucose Index on Carotid Atherosclerosis: A Prospective Cohort Study in Middle Aged and Elderly Low-Income in Rural Chinese.Risk management and healthcare policy · 2025Article
- Association between the non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) and cardiovascular outcomes in patients undergoing percutaneous coronary intervention: a retrospective study.Lipids in health and disease · 2024Article
- Sex-specific differences in the association between triglyceride glucose index and carotid plaque in a cardiovascular high-risk population: a cross-sectional study based on a Chinese community-dwelling population.Frontiers in cardiovascular medicine · 2024Article
- Non-linear association and benchmark dose of blood pressure on carotid artery intima-media thickening in a general population of southern China.Frontiers in cardiovascular medicine · 2024Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivePrevious studies linking Triglyceride Glucose (TyG) Index to carotid plaque have yielded inconsistent results. Moreover, related studies on the population of Japan are rare. This study aims to provide further results.
designA hospital-based cross-sectional study.
settingThe Shin Takeo Hospital.
participantsWe assessed 1904 Japanese participants (988 men and 916 women) whose mean age was 57±11.9 years, and those participants underwent health check-ups at Shinbuf Hospital at Shin Takeo Hospital from 1 April 2016 to 31 October 2017. METHODOLOGY: Carotid plaque, triglyceride and fasting glucose and other relevant indicators were collected. We used ultrasonography to evaluate carotid plaque. A multivariable logistic regression model and generalised additive model were used to evaluate the association between the TyG Index and carotid plaque. Subgroup and interaction analyses were validated for the consistency of these correlations.
resultsFollowing the adjustment of traditional carotid plaque risk factors, the non-linear relationship between the TyG Index and carotid plaque was investigated. Using a two-piecewise regression model, we calculated the inflection point to be 9.06. The OR and 95% CIs for the inflection points on the left and right sides were 1.70 (1.27 to 2.29) and 0.88 (0.52 to 1.47), respectively. According to the variables tested, the interactions between the TyG Index and all subgroup factors were analysed and significant interactions were not observed.
conclusionIn individuals who underwent a comprehensive check-up in Japan, the relationship between the TyG Index and carotid plaque is non-linear. When the TyG Index is less than 9.06, it is associated with carotid plaque.
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