ArticleJournal of neurointerventional surgery2023
Safety and effectiveness of the Woven EndoBridge (WEB) system for the treatment of wide necked bifurcation aneurysms: final 5 year results of the pivotal WEB Intra-saccular Therapy study (WEB-IT).
Article in Journal of neurointerventional surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Retreatment rate and strategies for recurrent and residual aneurysms after Woven EndoBridge (WEB) treatment: a comprehensive systematic review and meta-analysis.Neurosurgical review · 2025Pooled it
- Flow Diversion for Anterior Communicating Artery Aneurysms: Systematic Review and Meta-Analysis.Stroke (Hoboken, N.J.) · 2026Article
- Widening the treatment of shallow intracranial aneurysms with intrasaccular flow disruption: The flat WEB experience.The neuroradiology journal · 2026Article
- Contour device implantation for treatment of intracranial aneurysms in the basilar tip.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026Article
- Neurointerventional Advances in 2025.Stroke (Hoboken, N.J.) · 2026Article
- High-resolution CT angiography for follow-up evaluation of intracranial aneurysms treated with the Woven EndoBridge device: comparison with digital subtraction angiography.Journal of neurointerventional surgery · 2026Article
- Woven EndoBridge intrasaccular therapy for the treatment of unruptured wide-necked bifurcation aneurysms: a prospective study in a Chinese population.Chinese neurosurgical journal · 2026Article
- Factors influencing immediate post-angiographic occlusion outcomes in intracranial aneurysms treated with the woven endobridge device: a multi-center analysis and predictive model from the WorldWideWEB consortium.Neurosurgical review · 2025Article
- Woven Endobridge as a first-line strategy for posterior communicating artery aneurysms: enhanced applicability in fetal-type variants.Neuroradiology · 2025Article
- Mechanisms of Intracranial Aneurysm Rupture: An Integrative Review of Experimental and Clinical Evidence.Journal of clinical medicine · 2025Review
- Retrospective multicenter analysis of the Trenza Embolization Device for endovascular therapy of intracranial aneurysms: initial results and short-term follow-up.Journal of neurointerventional surgery · 2025Article
- Outcome Analysis and Early Concept Development to Identify the Most Suitable Woven EndoBridge Size Based on Various Shapes of Cerebral Aneurysms.Neurointervention · 2025Article
- The Woven EndoBridge for Wide-Neck Bifurcation Aneurysms: A Retrospective Study of 120 Cases with Expanded Indications Covering All Subtypes.Neurointervention · 2025Article
- 15 years of WEB embolization: a transformative journey in aneurysm treatment.Journal of neurointerventional surgery · 2025Article
- Optimal woven endobridge (WEB) device-aneurysm volume: using automated volumetric software to predict aneurysmal occlusion status after WEB treatment.Acta neurochirurgica · 2025Article
- Neck apposition is a key factor for aneurysm occlusion after Woven EndoBridge device embolization.Journal of neurointerventional surgery · 2025Article
- Microsurgical clipping of a recurrent anterior communicating artery aneurysm following WEB intrasaccular embolization: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Early Complete Obliteration of Recurrent Large Basilar Aneurysm by Combined Use of Additional Woven EndoBridge Device and Flow Diverter: A Case Report.Neurointervention · 2025Article
- WovenEndoBridge-assisted coiling: Step-by-step technical insights.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025Article
- Woven endobridge embolization versus microsurgical clipping for unruptured wide-neck cerebral aneurysms on middle cerebral artery bifurcation.BMC neurology · 2025Article
Corrections and comments
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Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe US Woven EndoBridge Intra-saccular Therapy (WEB-IT) study is a pivotal, prospective, single arm, investigational device exemption study to evaluate the safety and effectiveness of the WEB device for the treatment of wide neck bifurcation aneurysms (WNBAs). We present complete 5 year data for the cohort of 150 patients.
methods150 patients with WNBAs were enrolled at 21 US and six international centers. Imaging from the index procedure, 6 month, 1 year, 3 year, and 5 year follow-up were reviewed by a core laboratory. Adverse events were reviewed and adjudicated by a clinical events adjudicator.
results83 patients had 5 year follow-up imaging and 123 had clinical follow-up. No ruptured (0/9) or unruptured aneurysm (0/141) rebled or bled during follow-up. No new device or procedure related adverse events or serious adverse events were reported after 1 year. At 5 years, using the LOCF method, complete occlusion was observed in 58.1% and adequate occlusion in 87.2% of patients. For patients with both 1 year and 5 year occlusion statuses available, 76.8% (63/82) of aneurysms remained stable or improved with no retreatment. After 1 year, 18 aneurysms were retreated, 11 of which were adequately occluded at 1 year, and 15 of which were retreated in the absence of any deterioration in occlusion grade.
conclusionsFive year follow-up data from the WEB-IT study demonstrated that the WEB device was safe and effective when used in the treatment of WNBAs. Aneurysm occlusion rates achieved at 1 year follow-up were durable, with rates of progressive thrombosis far exceeding rates of recurrence over time.
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