Evidence map›Paper›PMID 37355095›Full record

ArticleAmerican journal of infection control2023

Association between ventilator-associated events and implementation of acute respiratory distress syndrome (ARDS) ventilator weaning protocol.

Gerard Marshall, Jennifer Sanguinet, Shreya Batra, Mary Jo Foreman, Justin Peruchini, Sarah Lopez, Rian De Guzman, Nancy Rivera, Todd Hightower, Cheryl Malone and 1 more

Abstract read
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Article in American journal of infection control, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Gerard MarshallSunrise Hospital and Medical Center, Las Vegas, NV, USA.
Jennifer SanguinetSunrise Hospital and Medical Center, Las Vegas, NV, USA. Electronic address: Jennifer.sanguinet@hcahealthcare.com.
Shreya BatraSunrise Hospital and Medical Center, Las Vegas, NV, USA.
Mary Jo ForemanSunrise Hospital and Medical Center, Las Vegas, NV, USA.
Justin PeruchiniSunrise Hospital and Medical Center, Las Vegas, NV, USA.
Sarah LopezSunrise Hospital and Medical Center, Las Vegas, NV, USA.
Rian De GuzmanSunrise Hospital and Medical Center, Las Vegas, NV, USA.
Nancy RiveraSunrise Hospital and Medical Center, Las Vegas, NV, USA.
Todd HightowerSunrise Hospital and Medical Center, Las Vegas, NV, USA.
Cheryl MaloneSunrise Hospital and Medical Center, Las Vegas, NV, USA.
Sheri StuckeSunrise Hospital and Medical Center, Las Vegas, NV, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute respiratory distress syndrome (ARDS) is a severe and life-threatening condition that can occur in critically ill patients. Mechanical ventilation is a commonly used intervention with ARDS patients, but weaning patients off the ventilator can be challenging. An ARDSnet-like ventilator weaning protocol was implemented with the goal of reducing triggers for ventilator-associated events (VAEs).

methodsThe implementation of the new protocol was used to complete a retrospective investigation of patient outcomes for 1,233 ventilator periods. Periods were included between April and December 2022 for any ventilated patient lasting at least 4 days. National Health Care Safety Network VAE criteria were used to surveille the patient data. Triggers were based on the positive end-expiratory pressure increases or fraction of inspired oxygen (FiO₂) increases. The preset weaning criteria was a reduction by 2 cmH

resultsOf the total 1,233 individual ventilator periods, VAE criteria were met in 10%. Of the total 126 periods with VAE, 39.2% met the criteria for appropriate protocol implementation. There was a statistically significant relationship between VAE identification and implementation of the protocol.

conclusionsThe implementation of a protocol for ventilator weaning affects the outcome of developing a VAE. The findings emphasize the importance of implementing the ARDS weaning protocol as a template to reduce the triggers for VAEs and improve overall patient outcomes.

Indexed as

Pneumonia, Ventilator-AssociatedVentilator WeaningHumansRespiration, ArtificialRetrospective StudiesVentilators, MechanicalBurnInfection related ventilator-associated complications (IVAC)Mechanical ventilationPossible ventilator-associated pneumonia (PVAP)TraumaVentilator-associated condition (VAC)

Identifiers

PMID37355095
PMCPMC10286560

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.