ArticleJapanese journal of radiology2023
A new workflow of the on-line 1.5-T MR-guided adaptive radiation therapy.
Article in Japanese journal of radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 9 citations in OpenAlex.
- Automated workflow for target volume propagation in online adaptive magnetic resonance guided radiotherapy for lung lesions using foundation models.Physics and imaging in radiation oncology · 2026Article
- Impact of bulk density assignment of bone on MRI-based abdominal region radiotherapy planning for MR-linac workflow.Journal of applied clinical medical physics · 2025Article
- Efficient strategy for magnetic resonance image-guided adaptive radiotherapy of rectal cancer using a library of reference plans.Physics and imaging in radiation oncology · 2025Article
- Feasibility of creating a daily adaptive plan using automatic DIR-created target and OARs contours in patients with prostate cancer magnetic-resonance-guided adaptive radiotherapy.Journal of radiation research · 2024Article
- Evaluation of clinical parallel workflow in online adaptive MR-guided Radiotherapy: A detailed assessment of treatment session times.Technical innovations & patient support in radiation oncology · 2024Article
- Beginning of clinical treatment using the 1.5 Tesla MR-Linac system in Japan: a narrative review.Translational cancer research · 2024Review
- Revolutionizing radiation therapy: the role of AI in clinical practice.Journal of radiation research · 2024Review
- A pilot study on interobserver variability in organ-at-risk contours in magnetic resonance imaging-guided online adaptive radiotherapy for pancreatic cancer.Frontiers in oncology · 2024Article
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Authors and funding
12 authors at 2 institutions in 1 country.
Funding
Abstract
purposeThe aim of this study was to develop a new workflow for 1.5-T magnetic resonance (MR)-guided on-line adaptive radiation therapy (MRgART) and assess its feasibility in achieving dose constraints. MATERIALS AND
methodsWe retrospectively evaluated the clinical data of patients who underwent on-line adaptive radiation therapy using a 1.5-T MR linear accelerator (MR-Linac). The workflow in MRgART was established by reviewing the disease site, number of fractions, and re-planning procedures. Five cases of prostate cancer were selected to evaluate the feasibility of the new workflow with respect to achieving dose constraints.
resultsBetween December 2021 and September 2022, 50 consecutive patients underwent MRgART using a 1.5-T MR-Linac. Of these, 20 had prostate cancer, 10 had hepatocellular carcinoma, 6 had pancreatic cancer, 5 had lymph node oligo-metastasis, 3 had renal cancer, 3 had bone metastasis, 2 had liver metastasis from colon cancer, and 1 had a mediastinal tumor. Among a total of 247 fractions, 235 (95%) were adapt-to-shape (ATS)-based re-planning. The median ATS re-planning time in all 50 cases was 17 min. In the feasibility study, all dose constraint sets were met in all 5 patients by ATS re-planning. Conversely, a total of 14 dose constraints in 5 patients could not be achieved by virtual plan without using adaptive re-planning. These dose constraints included the minimum dose received by the highest irradiated volume of 1 cc in the planning target volume and the maximum dose of the rectal/bladder wall.
conclusionA new workflow of 1.5-T MRgART was established and found to be feasible. Our evaluation of the dose constraint achievement demonstrated the effectiveness of the workflow.
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