Evidence map›Paper›PMID 37354239›Full record

Observational studyEuropean journal of pediatrics2023

Emergency medical services utilisation among febrile children attending emergency departments across Europe: an observational multicentre study.

Chantal D Tan, Clementien L Vermont, Joany M Zachariasse, Ulrich von Both, Irini Eleftheriou, Marieke Emonts, Michiel van der Flier, Jethro Herberg, Benno Kohlmaier, Michael Levin and 12 more

Open access · hybridAbstract readObservational StudyMulticenter Study
In one paragraph

Observational study in European journal of pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. The Role of Paramedics in Diagnosing Sandifer's Syndrome.Healthcare (Basel, Switzerland) · 2025
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 16 institutions in 6 countries.

Chantal D TanDepartment of General Paediatrics, Erasmus MC-Sophia Children's Hospital, Rotterdam, the Netherlands.
Clementien L VermontDepartment of Paediatric Infectious Diseases and Immunology, Erasmus MC-Sophia Children's Hospital, Rotterdam, the Netherlands.
Joany M ZachariasseDepartment of General Paediatrics, Erasmus MC-Sophia Children's Hospital, Rotterdam, the Netherlands.
Ulrich von BothDivision of Paediatric Infectious Diseases, Dr. Von Hauner Children's Hospital, University Hospital, Ludwig-Maximilians University, Munich, Germany.
Irini EleftheriouSecond Department of Paediatrics, P. and A. Kyriakou Children's Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Marieke EmontsPaediatric Immunology, Infectious Diseases & Allergy, Great North Children's Hospital, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, UK.
Michiel van der FlierSection of Paediatric Infectious Diseases, Laboratory of Medical Immunology, Radboud Center for Infectious Diseases, Radboud Institute for Molecular Life Sciences, RadboudUMC, Nijmegen, the Netherlands.
Jethro HerbergSection of Paediatric Infectious Diseases, Imperial College, London, UK.
Benno KohlmaierDepartment of General Paediatrics, Medical University of Graz, Graz, Austria.
Michael LevinSection of Paediatric Infectious Diseases, Imperial College, London, UK.
Emma LimPaediatric Immunology, Infectious Diseases & Allergy, Great North Children's Hospital, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, UK.
Ian K MaconochiePaediatric Emergency Medicine, Imperial College Healthcare Trust NHS, London, UK.
Federico Martinon-TorresGenetics, Vaccines, Infections and Paediatrics Research Group (GENVIP), Hospital Clínico Universitario de Santiago de Compostela, Santiago de Compostela, Spain.
Ruud G NijmanSection of Paediatric Infectious Diseases, Imperial College, London, UK.
Marko PokornDepartment of Infectious Diseases and Faculty of Medicine, University Medical Centre Ljubljana, University of Ljubljana, Ljubljana, Slovenia.
Irene Rivero-CalleGenetics, Vaccines, Infections and Paediatrics Research Group (GENVIP), Hospital Clínico Universitario de Santiago de Compostela, Santiago de Compostela, Spain.
Maria TsoliaSecond Department of Paediatrics, P. and A. Kyriakou Children's Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Werner ZenzDepartment of General Paediatrics, Medical University of Graz, Graz, Austria.
Dace ZavadskaDepartment of Paediatrics, Children Clinical University Hospital, Rīgas Stradiņa Universitāte, Riga, Latvia.
Henriëtte A Moll *Department of General Paediatrics, Erasmus MC-Sophia Children's Hospital, Rotterdam, the Netherlands.
Enitan D Carrol *Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK. edcarrol@liverpool.ac.uk.
PERFORM consortium (Personalised Risk assessment in febrile children to optimize Real-life Management across the European Union)
Erasmus MC - Sophia Children’s Hospital · NLImperial College London · GBMedical University of Graz · ATNewcastle University · GBNational and Kapodistrian University of Athens · GRPanagiotis & Aglaia Kyriakou Children's Hospital · GRGreat North Children's Hospital · GBImperial College Healthcare NHS Trust · GBLudwig-Maximilians-Universität München · DEWilhelmina Children's Hospital · NLAlder Hey Children's NHS Foundation Trust · GBGerman Center for Infection Research · DELjubljana University Medical Centre · SINIHR Newcastle Biomedical Research Centre · GBUniversity of Liverpool · GBUniversity of Ljubljana · SI

Funding

Horizon 2020 Framework Programme 848196
6 · The paper itself

Abstract

Children constitute 6-10% of all patients attending the emergency department (ED) by emergency medical services (EMS). However, discordant EMS use in children occurs in 37-61% with fever as an important risk factor. We aimed to describe EMS utilisation among febrile children attending European EDs. This study is part of an observational multicentre study assessing management and outcome in febrile children up to 18 years (MOFICHE) attending twelve EDs in eight European countries. Discordant EMS use was defined as the absence of markers of urgency including intermediate/high triage urgency, advanced diagnostics, treatment, and admission in children transferred by EMS. Multivariable logistic regression analyses were performed for the association between (1) EMS use and markers of urgency, and (2) patient characteristics and discordant EMS use after adjusting all analyses for the covariates age, gender, visiting hours, presenting symptoms, and ED setting. A total of 5464 (15%, range 0.1-42%) children attended the ED by EMS. Markers of urgency were more frequently present in the EMS group compared with the non-EMS group. Discordant EMS use occurred in 1601 children (29%, range 1-59%). Age and gender were not associated with discordant EMS use, whereas neurological symptoms were associated with less discordant EMS use (aOR 0.2, 95%CI 0.1-0.2), and attendance out of office hours was associated with more discordant EMS use (aOR 1.6, 95%CI 1.4-1.9). Settings with higher percentage of self-referrals to the ED had more discordant EMS use (p < 0.05).  Conclusion: There is large practice variation in EMS use in febrile children attending European EDs. Markers of urgency were more frequently present in children in the EMS group. However, discordant EMS use occurred in 29%. Further research is needed on non-medical factors influencing discordant EMS use in febrile children across Europe, so that pre-emptive strategies can be implemented. What is Known: •Children constitute around 6-10% of all patients attending the emergency department by emergency medical services. •Discordant EMS use occurs in 37-61% of all children, with fever as most common presenting symptom for discordant EMS use in children. What is New: •There is large practice variation in EMS use among febrile children across Europe with discordance EMS use occurring in 29% (range 1-59%), which was associated with attendance during out of office hours and with settings with higher percentage of self-referrals to the ED. •Future research is needed focusing on non-medical factors (socioeconomic status, parental preferences and past experience, healthcare systems, referral pathways, out of hours services provision) that influence discordant EMS use in febrile children across Europe.

Indexed as

Emergency Medical ServicesAdolescentChildEmergency Service, HospitalEuropeFeverHumansProspective StudiesTriageChildrenEmergency careEmergency medical servicesFeverPaediatrics

Identifiers

PMID37354239
PMCPMC10570223
OpenAlexW4381943733

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.