Evidence map›Paper›PMID 37353906›Full record

Trial reportThe journal of sexual medicine2023

A virtual, group-based mindfulness intervention for midlife and older women with low libido lowers sexual distress in a randomized controlled pilot study.

Holly N Thomas, Lori A Brotto, Flor de Abril Cameron, Jonathan Yabes, Rebecca C Thurston

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The journal of sexual medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Review
  6. Article
  7. Effects of Mindfulness-Based Intervention on Sexual Health in Menopause: A Systematic Review.International journal of sexual health : official journal of the World Association for Sexual Health · 2025
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Holly N ThomasDepartment of Medicine, University of Pittsburgh, Pittsburgh, PA 15217, United States.
Lori A BrottoDepartment of Obstetrics and Gynecology, University of British Columbia, Vancouver V5Z 4M2, Canada.
Flor de Abril CameronDepartment of Medicine, University of Pittsburgh, Pittsburgh, PA 15217, United States.
Jonathan YabesDepartment of Medicine, University of Pittsburgh, Pittsburgh, PA 15217, United States.
Rebecca C ThurstonDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15217, United States.
University of Pittsburgh · USUniversity of British Columbia · CA

Funding

University of Pittsburgh Clinical and Translational Science InstituteUL1TR001857 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2016 to 2025
$129.3M
Interdisciplinary Mentoring and Research in Womens Cardiovascular HealthK24HL123565 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI THURSTON, REBECCA C · 2014 to 2023
$1.0M
Adaptation and Pilot Testing of a Mindfulness-Based Behavioral Intervention for Older Women with Low Sexual DesireK23AG052628 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI THOMAS, HOLLY NICOLE · 2017 to 2021
$939k
NCATS NIH HHS UL1 TR001857NHLBI NIH HHS K24 HL123565NIA NIH HHS K23 AG052628
6 · The paper itself

Abstract

backgroundDistressing low libido is common among women and has significant negative impacts; mindfulness has shown promise to increase sexual desire in women with low libido, but existing interventions are not tailored to midlife and older women.

aimWe adapted a mindfulness intervention to meet the needs of this population and conducted a pilot randomized controlled trial to assess feasibility and acceptability.

methodsWomen aged ≥45 years with low libido were randomized to the mindfulness intervention or an education group that met over videoconferencing. The intervention included mindfulness instruction and practice, group discussion, and education on sexuality and aging. The education group included general information on menopause and health. OUTCOMES: We defined feasibility by the number of screened women who enrolled and completed their group. We defined acceptability as satisfaction with the group and likelihood of recommending it to another woman with low libido. We assessed sexual function (Female Sexual Function Index) and sexual distress (Female Sexual Distress Scale-Revised) at 6 weeks postconclusion.

resultsOf 81 women screened, 31 were randomized to mindfulness and 30 to education. Eighteen women in the intervention group and 23 in the control group attended at least 1 session. Time conflict was the main reason for nonattendance. Of the 41 women who started attending groups, 37 (90%) attended at least 5 sessions. In the mindfulness group, 73% of women were very or extremely satisfied. Women in the mindfulness group were more likely to recommend it to another person with low libido as compared with those in the education group (P = .031); 67% said that they would probably or definitely recommend it. There were no significant changes in sexual function in either group (mean Female Sexual Function Index score, 22.6 to 18.6 [P = .101] with mindfulness and 21.2 to 19.7 [P = .537] with education). Women in the mindfulness group had significant improvements in sexual distress (mean Female Sexual Distress Scale-Revised score, 27.1 to 19.7; P = .021) while women in the education group did not (19.0 to 15.8; P = .062). CLINICAL IMPLICATIONS: Mindfulness may reduce sexual distress in older women with low libido. STRENGTHS AND LIMITATIONS: This is the first trial testing mindfulness for midlife and older women with low libido.

conclusionA virtual mindfulness intervention for midlife and older women with low libido is feasible and acceptable and appears to improve sexual distress as compared with an education control; these findings provide data that can be used to design a larger clinical trial.

Indexed as

LibidoMindfulnessAgedFemaleHumansMenopausePilot ProjectsSexual Behavioragingfeasibility studieslibidomenopausemindfulnesspilot projectssexuality

Identifiers

PMID37353906
PMCPMC10390320
OpenAlexW4381838964

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.