ArticleScientific reports2023
Resistance training rejuvenates aging skin by reducing circulating inflammatory factors and enhancing dermal extracellular matrices.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 24 citations in OpenAlex.
- Skin aging: mechanisms, evaluation, and rejuvenation.The EMBO journal · 2026Review
- Advances in skin aging: integrating epigenetic, cellular, and immune mechanisms for targeted therapy.Immunity & ageing : I & A · 2026Review
- A Review of the Effects of Lifestyle Factors on Skin Aging.American journal of lifestyle medicine · 2026Review
- Exercise modulates redox homeostasis in cardiovascular and metabolic diseases: from bench to clinic.Cardiovascular diabetology · 2026Review
- Exercise modality-dependent mitochondrial respiratory capacity in satellite cells and conditioned serum-induced responses in cultured myotubes.Experimental physiology · 2026Article
- The impact of the six pillars of lifestyle medicine on the biology of skin aging.Frontiers in aging · 2026Review
- Dual modes of action: direct regulation and ceRNA-mediated mechanisms of ncRNAs in dermal fibroblast senescence.Frontiers in cell and developmental biology · 2026Review
- Skinspan: A Holistic Roadmap for Extending Skin Longevity With Evidence-Based Interventions.Journal of cosmetic dermatology · 2025Review
- Skin health and biological aging.Nature aging · 2025Review
- Advances in Longevity: The Intersection of Regenerative Medicine and Cosmetic Dermatology.Journal of cosmetic dermatology · 2025Review
- Combination of ferulic acid and exercise alleviates menopause symptoms and skin remodeling in ovariectomized rats.Nutrition research and practice · 2025Article
- No Associations Between Genetically Predicted Chronotype, Insomnia, Daytime Sleepiness, or Physical Activity and Acne Vulgaris: A Two-Sample Mendelian Randomization Study.Clinical, cosmetic and investigational dermatology · 2025Article
- The role of exercise in promoting lymphangiogenesis and extracellular matrix synthesis in lymphedema-induced tissue injury.Molecular biology reports · 2024Article
- Tailoring biomaterials for skin anti-aging.Materials today. Bio · 2024Review
- Untangling the Uncertain Role of Overactivation of the Renin-Angiotensin-Aldosterone System with the Aging Process Based on Sodium Wasting Human Models.International journal of molecular sciences · 2024Review
- Approaches in line with human physiology to prevent skin aging.Frontiers in physiology · 2023Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aerobic training (AT) is suggested to be an effective anti-aging strategy for skin aging. However, the respective effects of resistance training (RT) have not been studied. Therefore, we compared the effects of AT and RT on skin aging in a 16-week intervention in 61 healthy sedentary middle-aged Japanese women. Data from 56 women were available for analysis. Both interventions significantly improved skin elasticity and upper dermal structure, and RT also improved dermal thickness. After the training intervention, expression of dermal extracellular matrix-related genes was increased in normal human primary dermal fibroblasts. AT and RT had different effects on circulating levels of factors, such as cytokines, hormones in serum, and metabolites, and RT increased dermal biglycan (BGN). To our knowledge, this is the first report to show different effects of AT and RT on skin aging and identify the key factors involved in RT-induced skin rejuvenation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.