ArticleScientific reports2023
Association between dietary caffeine intake and severe headache or migraine in US adults.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- The impact of caffeine consumption on migraine: a systematic review.BMC neurology · 2026Pooled it
- Caffeine and Headache: Exploring the Multifaceted Relationship.Brain and behavior · 2026Review
- Article
- Three Successive Infusions: Scientific Insights Into a Traditional Green Tea Drinking Custom.Journal of food science · 2026Article
- Caffeine intake and late dry age-related macular degeneration: tea's protective role-insights from NHANES and Mendelian randomization.International journal of retina and vitreous · 2026Article
- The association between age at menarche and subsequent risk of chronic pain.Frontiers in global women's health · 2026Review
- Coffee Consumption is Associated with a High Prevalence of Headache in a Taiwanese Population Study.International journal of medical sciences · 2026Article
- Nutrition and Physical Activity in an Interdisciplinary Approach to Migraine: A Narrative Review.Nutrients · 2025Review
- Association between caffeine and the eGFR dip after initiation of SGLT2 inhibitors in adult patients.Physiological reports · 2025Article
- Burden of migraine among university students in the Middle East and North Africa: a cross-sectional study of prevalence, mental health comorbidities, and disability.BMC public health · 2025Article
- Internet use May be associated with the severity of headache in migraine patients: results from a Hungarian tertiary headache center.BMC public health · 2025Article
- Sex Related Differences in the Complex Relationship between Coffee, Caffeine and Atrial Fibrillation.Nutrients · 2023Review
- Caffeine use disorder and analgesic dependence in medication-overuse headache: insights into an underrecognized relationship.Frontiers in neurologyArticle
Corrections and comments
- Erratum issued
Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The relationship between current dietary caffeine intake and severe headache or migraine is controversial. Therefore, we investigated the association between dietary caffeine intake and severe headaches or migraines among American adults. This cross-sectional study included 8993 adults (aged ≥ 20 years) with a dietary caffeine intake from the National Health and Nutrition Examination Surveys of America from 1999 to 2004. Covariates, including age, race/ethnicity, body mass index, poverty-income ratio, educational level, marital status, hypertension, cancer, energy intake, protein intake, calcium intake, magnesium intake, iron intake, sodium intake, alcohol status, smoking status, and triglycerides, were adjusted in multivariate logistic regression models. In US adults, after adjusting for potential confounders, a 100 mg/day increase in dietary caffeine intake was associated with a 5% increase in the prevalence of severe headache or migraine (odds ratio [OR] 1.05, 95% confidence interval [CI] 1.02-1.07). Further, the prevalence of severe headache or migraine was 42% higher with caffeine intake of ≥ 400 mg/day than with caffeine intake of ≥ 0 to < 40 mg/day (OR 1.42, 95% CI 1.16-1.75). Conclusively, dietary caffeine intake is positively associated with severe headaches or migraines in US adults.
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