Evidence map›Paper›PMID 37353474›Full record

ArticleBiological research for nursing2024

Age Differences in Upper Gastrointestinal Symptoms and Vagal Modulation in Women With Irritable Bowel Syndrome.

Li Juen Chen, Robert Burr, Kevin Cain, Kendra Kamp, Margaret Heitkemper

Open access · greenAbstract read
In one paragraph

Article in Biological research for nursing, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 1 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Li Juen ChenDepartment of Biobehavioral Nursing and Health Informatics, School of Nursing, University of Washington, Seattle, WA, USA.
Robert BurrDepartment of Biobehavioral Nursing and Health Informatics, School of Nursing, University of Washington, Seattle, WA, USA.
Kevin CainCenter for Biomedical Statistics, University of Washington, Seattle, WA, USA.
Kendra KampDepartment of Biobehavioral Nursing and Health Informatics, School of Nursing, University of Washington, Seattle, WA, USA.ORCID 0000-0002-7753-3564
Margaret HeitkemperDepartment of Biobehavioral Nursing and Health Informatics, School of Nursing, University of Washington, Seattle, WA, USA.ORCID 0000-0002-2938-1842
University of Washington · US

Funding

NURSING MANAGEMENT OF IBS--IMPROVING OUTCOMESR01NR004142 · NINR · UNIVERSITY OF WASHINGTON · PI HEITKEMPER, MARGARET MCLEAN · 1996 to 2011
$5.5M
A Comprehensive Self-Management Intervention for individuals with Inflammatory Bowel DiseaseK23NR020044 · NINR · UNIVERSITY OF WASHINGTON · PI KAMP, KENDRA JOY · 2022 to 2024
$430k
NINR NIH HHS K23 NR020044NINR NIH HHS R01 NR004142
6 · The paper itself

Abstract

BACKGROUND/

aimsPatients with irritable bowel syndrome (IBS) often report upper gastrointestinal (GI) (e.g., nausea and heartburn), somatic, and emotional symptoms. This study seeks to examine the relationships among younger and older women with IBS and indicators of autonomic nervous system (ANS) function and daily nausea and heartburn symptoms.

methodsWomen were recruited through clinics and the community. Nocturnal heart rate variability (HRV) was obtained using ambulatory electrocardiogram Holter monitors. Individual symptom severity and frequency were collected using 28-day diaries. All variables were stratified by younger (<46 years) and older (≥46 years) age groups.

resultsEighty-nine women with IBS were included in this descriptive correlation study (

conclusionsAge-related differences in ANS function that are associated with nausea may portend unique opportunities to better understand the vagal dysregulation in women with IBS.

Indexed as

Irritable Bowel SyndromeAgedElectrocardiographyFemaleHeartburnHumansNauseaageheartburnheart rate variabilityirritable bowel syndromenausea

Identifiers

PMID37353474
PMCPMC10850873
OpenAlexW4381839364

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.