Evidence map›Paper›PMID 37353327›Full record

ArticleRespiratory care2023

Acute Hypercapnic Respiratory Failure in COPD.

Neil R MacIntyre

Open access · greenAbstract read
In one paragraph

Article in Respiratory care, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Epidemiological Trends and Projections of PMInternational journal of chronic obstructive pulmonary disease · 2026
    Article
  9. Observational
  10. Article
  11. Observational
  12. Review
  13. Article
  14. VENT-AVOID Trial: Avoiding Acute Hypercapnic Respiratory Failure!American journal of respiratory and critical care medicine · 2024
    Article
  15. Reply to TiruvoipatiAmerican journal of respiratory and critical care medicine · 2024
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Neil R MacIntyreDuke University Medical Center, Durham, North Carolina. neil.macintyre@duke.edu.
Duke Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

COPD is a progressive inflammatory process affecting both the airways and alveolar structures of the lungs. Exacerbations of COPD are episodes of acute worsening of this inflammatory process, often triggered by infections. The most severe exacerbations are characterized by substantial air trapping and inspiratory muscle overload, which leads to hypercapnic respiratory failure. Pharmacologic therapies focus on intense bronchodilator administration (usually by aerosol), corticosteroids, and antibiotics. Respiratory life support technologies are often needed for severe exacerbations and range from carefully titrated supplemental O

Indexed as

Noninvasive VentilationPulmonary Disease, Chronic ObstructiveRespiratory InsufficiencyHumansHypercapniaLungPositive-Pressure Respirationair trapping (intrinsic PEEP)COPDCOPD exacerbationshypercapnic respiratory failureinspiratory muscle overloadpositive-pressure ventilation (invasive and noninvasive)

Identifiers

PMID37353327
PMCPMC10289623
OpenAlexW4381738270

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.