Evidence map›Paper›PMID 37353306›Full record

ReviewClinical medicine (London, England)2023

Recent treatment advances and practical management of hepatitis D virus.

Kathryn Olsen, Sara Mahgoub, Sarah Al-Shakhshir, Akram Algieder, Sowsan Atabani, Ayman Bannaga, Ahmed M Elsharkawy

Abstract readReview
In one paragraph

Review in Clinical medicine (London, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Current perspectives of viral hepatitis.World journal of gastroenterology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kathryn OlsenLiver Unit, Queen Elizabeth Hospital Birmingham, Birmingham, UK.
Sara MahgoubLiver Unit, Queen, Elizabeth Hospital Birmingham, Birmingham, UK.
Sarah Al-ShakhshirLiver Unit, Queen, Elizabeth Hospital Birmingham, Birmingham, UK.
Akram AlgiederLiver Unit, Queen, Elizabeth Hospital Birmingham, Birmingham, UK.
Sowsan AtabaniQueen Elizabeth Hospital Birmingham, Birmingham, UK.
Ayman BannagaQueen Elizabeth Hospital Birmingham, Birmingham, UK aymanbannaga@yahoo.com.
Ahmed M ElsharkawyQueen Elizabeth Hospital Birmingham, Birmingham, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis D virus (HDV), also referred to as hepatitis delta virus, is the smallest virus capable of causing human disease. It is unable to replicate on its own and can only propagate in the presence of hepatitis B virus (HBV). Infection with both HBV and HDV frequently results in more severe disease than HBV alone, with higher instances of cirrhosis, liver failure and hepatocellular carcinoma (HCC). Thus, there is a need for effective treatment for HDV; however, currently approved treatment options are very limited both in terms of their efficacy and availability. This makes the management of HDV a challenge for physicians. In this review, we look at the background, diagnosis and treatment of HDV, informed by our hospital data, to set out the optimal management of HDV; we also explore novel treatment options for this disease.

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsAntiviral AgentsHepatitis B virusHepatitis Delta VirusHumansAntiviral AgentsbulevirtideHepatitis D viruslonafarnibnucleic acid polymer REP 2139pegylated interferon

Identifiers

PMID37353306
PMCPMC10541033

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.